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Table 5 Analysis of the main outcomes

From: Arterial/venous thrombosis, fetal loss and stillbirth in pregnant women with systemic lupus erythematosus versus primary and secondary antiphospholipid syndrome: a systematic review and meta-analysis

Outcomes assessed

No of studies involved (n)

RR with 95% CIs

P value

I2 (%)

SLE versus APS

 Arterial and venous thrombosis

3

3.95 [1.28–12.16]

0.02

57

 Fetal loss

4

4.49 [2.09–9.64]

0.0001

6

 Stillbirth

2

6.65 [2.14–20.60]

0.001

0

 Low for gestational age

3

1.73 [0.77–3.87]

0.18

30

 Premature delivery

5

1.07 [0.67–1.70]

0.79

31

SLE versus PAPS

 Arterial and venous thrombosis

3

4.15 [1.00–17.16]

0.05

54

 Fetal loss

3

4.89 [1.79–13.40]

0.002

6

SLE versus SAPS

 Arterial and venous thrombosis

2

7.73 [2.22–26.89]

0.001

0

 Fetal loss

5

5.92 [2.06–16.98]

0.0009

52

 Stillbirth

3

8.07 [2.81–23.15]

0.0001

0

 Low for gestational age

2

0.98 [0.40–2.36]

0.96

0

 Premature delivery

5

1.23 [0.54–2.80]

0.62

69

PAPS versus SAPS

 Fetal loss

4

0.86 [0.34–2.21]

0.76

77

 Arterial and venous thrombosis

3

1.11 [0.86–1.43]

0.43

0

  1. Abbreviations: SLE systemic lupus erythematosus, APS antiphospholipid syndrome, PAPS primary antiphospholipid syndrome, SAPS secondary antiphospholipid syndrome, RR risk ratios, CIs confidence intervals