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Table 3 Maternal characteristics and clinical factors associated with early- and late-onset preeclampsia

From: Population-based trends and risk factors of early- and late-onset preeclampsia in Taiwan 2001–2014

Characteristics

Ongoing pregnancies at 20 weeks

Early-onset preeclampsia

Ongoing pregnancies at 34 weeks

Late-onset preeclampsia

n = 2,884,347

n = 13,883

Rate per 1000

(95% CI)

n = 2,814,742

n = 18,909

Rate per 1000

(95% CI)

Age at delivery

 15–24

525,457

1305

2.48

(2.35–2.62)

513,581

2447

4.76

(4.58–4.95)

 25–34

1,956,147

8688

4.44

(4.35–4.53)

1,914,210

12,155

6.35

(6.24–6.46)

 35–55

402,743

3890

9.66

(9.36–9.96)

386,951

4307

11.13

(10.8–11.5)

Number of prior 20 weeks births (parity)

 0

1,938,341

9559

4.93

(4.83–5.03)

1,893,197

14,611

7.72

(7.59–7.84)

  ≥ 1

946,006

4324

4.57

(4.43–4.71)

921,545

4298

4.66

(4.52–4.80)

Place of residence

 Urban

1681,534

7988

4.75

(4.65–4.85)

1,641,570

11,169

6.8

(6.68–6.93)

 Suburban

826,656

4368

5.28

(5.13–5.44)

806,062

5645

7

(6.82–7.19)

 Rural

192,141

1027

5.35

(5.02–5.67)

186,732

1403

7.51

(7.12–7.91)

 Unknown

184,016

500

2.72

(2.48–2.96)

180,378

692

3.84

(3.55–4.12)

Income levels

 Quintile 1

558,314

2689

4.82

(4.63–5.00)

542,450

3825

7.05

(6.83–7.27)

 Quintile 2

516,131

2560

4.96

(4.77–5.15)

503,177

3441

6.84

(6.61–7.07)

 Quintile 3

566,360

3097

5.47

(5.28–5.66)

553,016

4140

7.49

(7.26–7.71)

 Quintile 4

527,626

2508

4.75

(4.57–4.94)

516,050

3499

6.78

(6.56–7.01)

 Quintile 5

540,007

2554

4.73

(4.55–4.91)

527,737

3351

6.35

(6.13–6.56)

 Unknown

175,909

475

2.7

(2.46–2.94)

172,312

653

3.79

(3.50–4.08)

Acute Coronary syndrome

 No

2,878,429

13,809

4.8

(4.72–4.88)

2,809,040

18,854

6.71

(6.62–6.81)

 Yes

5918

74

12.5

(9.66–15.4)

5702

55

9.65

(7.10–12.2)

Chronic ischemic heart disease

 No

2,877,398

13,767

4.78

(4.70–4.86)

2,808,117

18,801

6.7

(6.60–6.79)

 Yes

6949

116

16.69

(13.7–19.7)

6625

108

16.3

(13.2–19.4)

Stroke

 No

2,877,911

13,792

4.79

(4.71–4.87)

2,808,569

18,824

6.7

(6.61–6.80)

 Yes

6436

91

14.14

(11.2–17.0)

6173

85

13.77

(10.8–16.7)

Diabetes mellitus

 No

2,856,198

13,164

4.61

(4.53–4.69)

2,788,463

18,256

6.55

(6.45–6.64)

 Yes

28,149

719

25.54

(23.7–27.4)

26,279

653

24.85

(22.9–26.8)

Chronic hypertension

 No

2,862,222

11,671

4.08

(4.00–4.15)

2,796,074

17,471

6.25

(6.16–6.34)

 Yes

22,125

2212

99.98

(95.8–104)

18,668

1438

77.03

(73.0–81.0)

Hyperthyroidism

 No

2,813,030

13,316

4.73

(4.65–4.81)

2,745,618

18,231

6.64

(6.54–6.74)

 Yes

71,317

567

7.95

(7.30–8.60)

69,124

678

9.81

(9.07–10.5)