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Table 4 Associationsa between common carotid artery intima-media thickness, physical predictors, and significant metabolic predictors

From: Common carotid artery intima-media thickness increases throughout the pregnancy cycle: a prospective cohort study

Predictor

Unadjusted

 

Model 1b

Model 2b

Model 3b

 

ß (SE)

P-value

ß (SE)

P-value

ß (SE)

P-value

ß (SE)

P-value

Trimester 1

Ref

 

Ref

 

Ref

 

Ref

 

Trimester 2

0.001 (.01)

0.89

0.001 (.01)

0.89

0.002 (.01)

0.85

0.007 (.01)

0.56

Trimester 3

0.013 (.01)

0.24

0.013 (.01)

0.24

0.009 (.01)

0.43

0.022 (.02)

0.22

Postpartum

0.027 (.01)c

0.02

0.027 (.01) c

0.02

0.026 (.01)cd

0.03

0.031 (.01)c

0.01

Age (yr)

  

0.004 (.00)

0.03

0.004 (.00)

0.02

0.003 (.00)

0.08

Pre-pregnancy BMI (kg/m2)

  

−0.001 (.00)

0.78

−0.002 (.00)

0.45

0.000 (.00)

0.93

SBP (mm Hg)

    

0.001 (.00)

0.08

  

Weight (kg)

      

−0.000 (.00)

0.66

Predictor

Model 4b

Model 5 b

Model 6b

Model 7b

 

ß (SE)

P-value

ß (SE)

P-value

ß (SE)

P-value

ß (SE)

P-value

Trimester 1

Ref

 

Ref

 

Ref

 

Ref

 

Trimester 2

0.016 (.01)

0.19

0.018 (.01)

0.17

0.007 (.01)

0.59

0.009 (.01)

0.51

Trimester 3

0.042 (.02)c

0.04

0.041 (.02)c

0.046

0.027 (.02)

0.19

0.033 (.02)c

0.13

Postpartum

0.036 (.01)d

0.003

0.035 (.01)d

0.005

0.034 (.01)c

0.006

0.027 (.01)d

0.03

Age (years)

0.002 (.00)

0.11

0.003 (.00)

0.07

0.003 (.002)

0.05

0.003 (.00)

0.12

Pre-pregnancy BMI (kg/m2)

−0.001 (.00)

0.70

−0.002 (.00)

0.35

−0.004 (.00)

0.15

−0.002 (.00)

0.55

Weight change (kg)

−0.002 (.00)

0.13

−0.002 (.00)

0.07

−0.002 (.00)

0.06

−0.002 (.00)

0.08

SBP (mmHg)

  

0.001 (.00)

0.04

0.001 (.00)

0.04

0.001 (.00)

0.03

Inter-adventitial diameter

    

0.026 (.01)

0.02

0.017 (.01)

0.17

Log HOMA-IR

      

−0.028 (.01)

0.03

  1. aLinear mixed models
  2. bModel 1: Adjusted for age & pre-pregnancy BMI. Model 2: Model 1 plus SBP. Model 3: Model 1 plus weight. Model 4: Model 1 plus weight change. Model 5: Model 1 plus SBP and weight change. Model 6: Model 5 plus inter-adventitial diameter. Model 7: Model 6 plus HOMA-IR
  3. cDifferent from second trimester at p < .05. dDifferent from third trimester at p < .05
  4. BMI is body mass index. SBP is systolic blood pressure. Weight change is from pre-pregnancy weight. β represents change in millimeters
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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