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Table 2 Associationsa between inter-adventitial diameter, physical predictors, and significant metabolic predictors

From: Common carotid artery intima-media thickness increases throughout the pregnancy cycle: a prospective cohort study

Predictor

Unadjusted

Model 1b

Model 2b

 

ß (SE)

P-value

ß (SE)

P-value

ß (SE)

P-value

Trimester 1

Ref

 

Ref

 

Ref

 

Trimester 2

0.361 (.07)c

0.0001

0.361 (.07)c

< 0.0001

0.389 (.07)c

< 0.001

Trimester 3

0.498 (.07)cd

0.0001

0.499 (.07)cd

< 0.0001

0.511 (.07)c

< 0.001

Postpartum

−0.015 (.05)

0.74

−0.014 (.05)

0.76

0.010 (.04)

0.81

Age (years)

  

−0.004 (.02)

0.81

−0.003 (.02)

0.83

Pre-pregnancy BMI (kg/m2)

  

0.046 (.02)

0.06

0.042 (.02)

0.09

SBP (mmHG)

    

0.004 (.00)

0.29

Predictor

Model 3b

Model 4b

Model 5b

 

ß (SE)

P-value

ß (SE)

P-value

ß (SE)

P-value

Trimester 1

Ref

 

Ref

0.84

Ref

 

Trimester 2

0.294 (.09)c

0.001

0.321 (.09)c

< 0.001

0.456 (.07)c

< 0.0001

Trimester 3

0.338 (.13)c

0.009

0.392 (.14)c

0.008

0.683 (.12)cd

< 0.0001

Postpartum

−0.032 (.05)

0.49

−0.020 (.05)

0.69

− 0.029 (.04)

0.44

Age (years)

0.004 (.02)

0.82

− 0.001 (.02)

0.93

−0.006 (.02)

0.73

Pre-pregnancy BMI (kg/m2)

0.013 (.03)

0.67

0.047 (.02)

0.06

0.006 (.03)

0.85

Weight (kg)

0.015 (.01)

0.08

  

0.011 (.01)

0.12

Weight change (kg)

  

0.010 (.01)

0.29

  

Triglycerides (mg/dl)

    

−0.002 (.00)

< 0.0001

Log hsCRP (mg/L)

    

0.070 (.02)

0.0002

  1. aLinear mixed models
  2. bModel 1: Adjusted for age & pre-pregnancy BMI. Model 2: Model 1 plus SBP. Model 3: Model 1 plus weight. Model 4: Model 1 plus weight change. Model 5: Model 3 plus triglycerides and Log hsCRP
  3. cDifferent from postpartum at p < .01. dDifferent from second trimester at p < .05
  4. Weight change is from pre-pregnancy weight. β represents change in millimeters
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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