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Table 3 Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV)

From: Development of a melting-curve based multiplex real-time PCR assay for simultaneous detection of Streptococcus agalactiae and genes encoding resistance to macrolides and lincosamides

Multiplex real-time PCR

Culturea

Total

 

Positive

Negative

 

Positive

11

4

15

Negative

1

86

87

Total

12

90

102

Sensitivity (95% CI)b

91.7% (59.7–99.5%)

Specificity (95% CI)b

95.5% (88.4–98.6%)

PPV (95% CI)b

73.3% (44.8–91.1%)

NPV (95% CI)b

98.9% (92.9–99.9%)

  1. aStandard routine culture of vaginal-rectal swab specimen collected from pregnant women at 35–37 weeks of gestation; bValues calculated with 95% confidence interval (CI) using the program available at http://faculty.vassar.edu/lowry/clin1.html
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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