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Table 4 Obstetric and neonatal outcomes among women with and without schizophrenia during delivery hospitalizations (N=23,357,461)

From: Adverse obstetric and neonatal outcomes complicated by psychosis among pregnant women in the United States

Obstetric and neonatal outcomes

Women

OR (95% CI)

With schizophrenia (N = 14,125)

Without psychosis (N = 23,343,336)

Unadjusted

Adjusteda

Adjustedb

n

%

n

%

Death during hospitalizations

≤10 c

0.04

1,468

0.01

5.15 (0.73, 36.61)

3.21 (0.45, 23.11)

2.23 (0.30, 16.80)

Cesarean delivery

5,544

39.25

7,718,434

33.06

1.31 (1.22, 1.41)

1.22 (1.13, 1.31)

1.16 (1.08, 1.25)

Length of stay, mean (SE), day

 Vaginal birth

3.55 (0.48)

2.53 (0.01)

NA

NA

NA

 Cesarean delivery

4.66 (0.19)

3.55 (0.02)

NA

NA

NA

Length of stay >6 day

 Vaginal birth

25

0.18

9,526

0.04

4.73 (1.93, 11.59)

3.86 (1.58, 9.41)

3.01 (1.11, 8.13)

 Cesarean delivery

547

3.87

245,416

1.05

3.34 (2.70, 4.12)

2.71 (2.19, 3.36)

2.33 (1.86, 2.93)

Induction of labor

2,444

17.30

4,247,666

18.20

0.93 (0.85, 1.03)

0.97 (0.88, 1.07)

0.98 (0.89, 1.09)

Antepartum hemorrhage

422

2.99

356,821

1.53

1.98 (1.61, 2.44)

1.74 (1.41, 2.15)

1.18 (0.96, 1.46)

 Placental abruption

355

2.51

246,768

1.06

2.43 (1.93, 3.04)

2.08 (1.66, 2.62)

1.34 (1.06, 1.68)

Postpartum hemorrhage

446

3.16

654,043

2.80

1.14 (0.93, 1.39)

1.13 (0.93, 1.39)

1.09 (0.89, 1.34)

Spontaneous delivery <37-week gestation

2,022

14.32

1,692,651

7.25

2.14 (1.92, 2.39)

1.85 (1.65, 2.06)

1.42 (1.26, 1.59)

Stillbirth

192

1.36

153,045

0.66

2.09 (1.54, 2.83)

1.62 (1.19, 2.19)

1.28 (0.94, 1.74)

Premature rupture of membranes

803

5.68

904,679

3.88

1.50 (1.28, 1.76)

1.44 (1.24, 1.69)

1.31 (1.12, 1.53)

Excessive fetal growth

237

1.68

609,142

2.61

0.64 (0.49, 0.84)

0.72 (0.55, 0.95)

0.87 (0.66, 1.14)

Poor fetal growth

560

3.96

507,269

2.17

1.86 (1.54, 2.24)

1.61 (1.33, 1.94)

1.10 (0.91, 1.33)

Fetal distress

2,590

18.34

3,342,430

14.32

1.34 (1.22, 1.49)

1.22 (1.11, 1.35)

1.13 (1.03, 1.25)

Fetal abnormalities

373

2.64

337,978

1.45

1.85 (1.50, 2.28)

1.75 (1.41, 2.16)

1.34 (1.08, 1.66)

  1. Abbreviations: SE standard error, OR odds ratio, CI confidence interval
  2. aAdjusted for maternal age (continuous), race, median household income quartiles, hospital location, hospital region, and year
  3. bFurther adjusted for ever smoking, alcohol/substance abuse, and pregnancy-related hypertension
  4. cHCUP privacy protection requirements do not allow the reporting of data where there are less than or equal to 10 individual records in a given cell