Skip to main content

Table 4 Results of the linear regression analysis modelling the association between pregnancies and serum ferritin

From: Do pregnancies reduce iron overload in HFE hemochromatosis women? results from an observational prospective study

Variables

Univariable analysis

Multivariable analysis

e β

95% CI

P

e β

95% CI

P

No. of pregnancies

 0

1.00

  

1.00

  

 1 or 2

1.25

[0.82–1.91]

0.288

1.03

[0.67–1.57]

0.902

  ≥ 3

1.39

[0.91–2.13]

0.126

1.02

[0.66–1.57]

0.944

Age at diagnosis

  < 60 y.a

1.00

  

1.00

  

  ≥ 60 y.

1.35

[1.04–1.73]

0.026

1.20

[0.89–1.62]

0.230

Body mass index

  < 25 kg/m2

1.00

     

  ≥ 25 kg/m2

1.13

[0.86–1.48]

0.387

–

  

Alcohol intake

 

 Non excessive

1.00

  

1.00

  

 Excessiveb

2.38

[1.34–4.20]

0.003

2.06

[1.11–3.85]

0.023

Menopause

 No

1.00

  

1.00

  

 Yes

1.55

[1.20–2.00]

< 0.001

1.39

[1.03–1.87]

0.032

Regular blood donations

 No

1.00

     

 Yes

0.84

[0.64–1.11]

0.219

–

  

Chronic bleedings

 No

1.00

     

 Yes

0.96

[0.46–1.99]

0.904

–

  

Blood transfusions

 No

1.00

     

 Yes

1.02

[0.69–1.50]

0.938

–

  
  1. aClassical cut-off for describing the beginning of the expression of HFE hemochromatosis in women
  2. bDaily consumption ≥ 2 glasses/day or 14 glasses/week in women (World Health Organization definition)
  3. Univariable analysis for pregnancy: global P-value = 0.293
Back to article page

BMC Pregnancy and Childbirth

ISSN: 1471-2393

Contact us