Table 1 Baseline characteristics of the p.Cys282Tyr homozygous hemochromatosis women according to the number of pregnancies that women had prior to entry into the phlebotomy program
Variables | All women | Number of pregnancies: 0 | Number of pregnancies: 1 or 2 | Number of pregnancies: ≥ 3 | P * | ||||
|---|---|---|---|---|---|---|---|---|---|
n | % | n | % | n | % | n | % | ||
Number of women | 137 | 14 | 65 | 58 | |||||
Age at diagnosis (n = 137) | |||||||||
≥ 60 ya | 41 | 29.9% | 2 | 14.3% | 16 | 24.6% | 23 | 39.7% | 0.077 |
< 60 y. | 96 | 70.1% | 12 | 85.7% | 49 | 75.4% | 35 | 60.3% | |
Body mass index (n = 131) | |||||||||
≥ 25 kg/m2 | 39 | 29.8% | 2 | 14.3% | 19 | 30.6% | 18 | 32.7% | 0.395 |
< 25 kg/m2 | 92 | 70.2% | 12 | 85.7% | 43 | 69.4% | 37 | 67.3% | |
Alcohol intake (n = 134) | |||||||||
Excessiveb | 6 | 4.5% | 0 | 0.0% | 2 | 3.1% | 4 | 7.0% | 0.418 |
Non excessive | 128 | 95.5% | 13 | 100.0% | 62 | 96.9% | 53 | 93.0% | |
Menopause (n = 126) | |||||||||
Yes | 80 | 63.5% | 3 | 21.4% | 36 | 66.7% | 41 | 70.7% | 0.002 |
No | 46 | 36.5% | 11 | 78.6% | 18 | 33.3% | 17 | 29.3% | |
Regular blood donations (n = 136) | |||||||||
Yes | 37 | 27.2% | 5 | 35.7% | 15 | 23.1% | 17 | 29.8% | 0.530 |
No | 99 | 72.8% | 9 | 64.3% | 50 | 76.9% | 40 | 70.2% | |
Chronic bleedings (n = 135) | |||||||||
Yes | 4 | 3.0% | 2 | 14.3% | 0 | 0.0% | 2 | 3.4% | 0.313 |
No | 131 | 97.0% | 12 | 85.7% | 63 | 100.0% | 56 | 96.6% | |
Blood transfusions (n = 134) | |||||||||
Yes | 15 | 11.2% | 1 | 7.1% | 6 | 9.7% | 8 | 13.8% | 0.681 |
No | 119 | 88.8% | 13 | 92.9% | 56 | 90.3% | 50 | 86.2% | |