| |
Small for gestational agea
|
Preterm delivery (< 37 weeks)b
|
Low birth weight (< 2500 g)c
|
Pregnancy lossd
|
|---|
| |
OR
|
CI 95%
|
OR
|
CI 95%
|
OR
|
CI 95%
|
OR
|
CI 95%
|
|---|
|
T1 25OHDe
|
|
Continuous nmol/L
|
1.003
|
0.99–1.01
|
0.996
|
0.99–1.01
|
0.999
|
0.99–1.01
|
0.989*
|
0.98–1.00
|
|
< 30 (ref)
|
1.0
| |
1.0
| |
1.0
| |
1.0
| |
|
30–49.9
|
1.078
|
0.44–2.66
|
1.647
|
0.63–4.33
|
2.549
|
0.88–7.38
|
1.030
|
0.44–2.41
|
|
50–74.9
|
1.632
|
0.69–3.85
|
1.260
|
0.47–3.36
|
2.287
|
0.77–6.83
|
0.688
|
0.29–1.62
|
|
75–99-9
|
1.292
|
0.51–3.27
|
1.332
|
0.48–3.73
|
1.665
|
0.51–5.49
|
0.809
|
0.33–1.96
|
|
≥ 100
|
1.294
|
0.38–4.42
|
0.502
|
0.09–2.72
|
1.255
|
0.22–7.27
|
0.000f
| |
|
T3 25OHDe
|
|
< 30 (ref)
|
1.0
| |
1.0
| |
1.0
| | | |
|
30–49.9
|
0.771
|
0.34–1.75
|
0.302
|
0.08–1.14
|
0.071*
|
0.01–0.63
| | |
|
50–74.9
|
0.623
|
0.27–1.45
|
0.933
|
0.31–2.79
|
0.584
|
0.17–1.98
| | |
|
75–99-9
|
0.657
|
0.27–1.61
|
0.614
|
0.18–2.14
|
0.237
|
0.06–1.01
| | |
|
≥ 100
|
0.318*
|
0.11–0.90
|
0.446
|
0.11–1.76
|
0.215*
|
0.05–0.97
| | |
|
Δ25OHDg
|
|
Large increase (≥ 30 nmol/L) (ref)
|
1.0
| |
1.0
| |
1.0
| | | |
|
Small increase (0–30 nmol/L)
|
2.564*
|
1.16–5.67
|
2.905*
|
1.01–8.34
|
3.122
|
0.97–10.09
| | |
|
Decrease (< 0 nmol/L)
|
3.679**
|
1.60–8.44
|
2.894
|
0.95–8.85
|
4.722*
|
1.37–16.28
| | |
- T1 first trimester, T3 third trimester, 25OHD 25-hydroxyvitamin D
- *p < 0.05 **p < 0.01
- aModels include 92 (T1) and 80 (T3 and Δ25OHD) cases of small for gestational age
- bModels include 77 (T1) and 43 (T3 and Δ25OHD) cases of preterm delivery
- cModels include 57 (T1) and 31 (T3 and Δ25OHD) cases of low birth weight
- dModels include 96 cases of pregnancy loss
- eAdjusted for education, origin, season of conception and BMI at T1. Pregnancy loss models are also adjusted for gestational age at registration for antenatal care
- fNo case of pregnancy loss in category
- gAdjusted for education, origin, season of conception, BMI at T1 and 25OHD at T1
