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Table 5 Composite primary and secondary outcomes* and mean umbilical cord arterial and venous pH values in the second twin according to twin-to-twin time interval ≤ 30 min or > 30 min

From: The effect of twin-to-twin delivery time intervals on neonatal outcome for second twins

 

0–30 min

N = 360

> 30 min

N = 167

p-value

Primary composite outcome

5 (1.4)

9 (5.4)

0.016

 pH < 7.05 and BE < −12 or pH < 7.00

3/290 (1)

9/136 (6.6)

0.002

 Apgar score < 4 at 5 min

2/357 (0.6)

0

1.0

 Perinatal mortality

2 (0.6)

0

1.0

 Neonatal mortality

0

0

1.0

Secondary composite outcome

61 (16.9)

31 (18.6)

0.71

 Apgar < 7 at 5 min

8 (2.2)

1 (0.6)

0.28

 pH < 7.10

18/290

22/136

0.002

 Admitted to NICU

88/360

35/167

0.44

 NICU, mean (SD), median, (range) days

11 (7.2)

10 (1–35)

12 (7.7)

9 (2–37)

0.26

 NICU > 7 days

54/88

22/35

1.0

 IRDS

4/360

1/167

1.0

 TTN

6/360

4/167

0.73

 Septicemia

2/360

0/167

1.0

 NEC

1/360

0/167

1.0

 Assisted ventilation

21/360

9/167

1.0

 Mean a-pH (SD)

7.23 (0.08)

N = 290

7.20 (0.09)

N = 136

< 0.0001

 Mean v-pH (SD)

7.29 (0.08)

N = 284

7.27 (0.09)

N = 140

0.016

  1. Values are n (%) unless otherwise stated
  2. BE Base Excess, NICU Neonatal Intensive Care Unit, IRDS Infant Respiratory Distress Syndrome, TTN Transient Tachypnea of the Newborn, NEC Necrotizing Enterocolitis, a-pH umbilical cord arterial pH, v-pH umbilical cord venous pH, BE Base Excess, SD standard deviation
  3. aas defined in Methods