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Table 3 Joint Effects of Pre-pregnancy Maternal BMI and GWG on Preeclampsia and Subtypes in Different Groups (N=9863)

From: Pre-pregnancy BMI, gestational weight gain and risk of preeclampsia: a birth cohort study in Lanzhou, China

Pre-pregnancy BMI

Weight Gain During Pregnancy (GWG) by IOM Guidelines

 

Not Excessive

Excessivea

Pinteraction

Cases

Controls

ORb (95%CI)

Cases

Controls

ORb (95% CI)

 

Preeclampsia

0.69

 Underweight

19

1234

0.75 (0.44-1.27)

27

824

1.65 (1.03-2.64)

 

 Normal weight

65

3054

1.00

156

3424

2.16 (1.60-2.92)

 

 Overweight/obese

11

219

2.10 (1.08-4.06)

69

761

3.78 (2.65-5.41)

 

M-PE

0.87

 Underweight

10

1234

1.16 (0.54-2.49)

14

824

2.42 (1.21-4.84)

 

 Normal weight

21

3054

1.00

65

3424

2.68 (1.62-4.42)

 

 Overweight/obese

2

219

1.22 (0.28-5.27)

29

761

4.82 (2.71-8.59)

 

S-PE

0.47

 Underweight

9

1234

0.55 (0.26-1.13)

13

824

1.26 (0.66-2.38)

 

 Normal weight

44

3054

1.00

91

3424

1.94 (1.34-2.82)

 

 Overweight/obese

9

219

2.45 (1.17-5.13)

40

761

3.22 (2.06-5.03)

 

EOPE

0.11

 Underweight

2

1234

0.51 (0.11-2.31)

2

824

0.81 (0.18-3.73)

 

 Normal weight

11

3054

1.00

18

3424

1.61 (0.75-3.45)

 

 Overweight/obese

4

219

4.48 (1.40-14.31)

6

761

1.97 (0.72-5.37)

 

LOPE

0.80

 Underweight

17

1234

0.80 (0.46-1.40)

25

824

1.81 (1.10-2.97)

 

 Normal weight

54

3054

1.00

138

3424

2.27 (1.64-3.15)

 

 Overweight/obese

7

219

1.59 (0.71-3.56)

63

761

4.11 (2.81-6.03)

 
  1. aExcessive weight gain: weight gain above the IOM recommendations, defined as weight gain during pregnancy over 18 kg, 16 kg, and 11.5 kg for underweight, normal weight, and overweight women, respectively
  2. bAdjusted for maternal age, maternal employment during pregnancy, education level, monthly household income, newborn gender, parity, twin status, family history of hypertension