Outcome | GA category (weeks) | Number of studies | Â | CS (n/N) | VD (n/N) | OR (95% CI) for CS | I2 (%) | GRADE Quality of the evidence* |
---|---|---|---|---|---|---|---|---|
Neonatal death or Severe Brain Injury in survivors | 24+0–27+6 | 2 | First twin (cephalic) | 1/6 | 4/8 | OR 0.35 (0.00–92.61) | 76 | Very Low |
Second twin (non-cephalic) | 3/7 | 2/6 | OR 1.69 (0.04–72.81) | 55 | ||||
Both twins | 4/13 | 6/14 | OR 0.83 (0.05–13.43) | 56 | ||||
Neonatal death | 24+0–27+6 | 2 | First twin (cephalic) | 0/7 | 2/10 | OR 0.36 (0.03–4.40) | 0 | Very low |
Second twin (non-cephalic) | 2/8 | 2/9 | OR 1.31 (0.02–79.60) | 66 | ||||
Both twins | 2/15 | 4/19 | OR 0.73 (0.10–5.46) | 26 | ||||
Severe Brain Injury in survivors | 24+0–27+6 | 2 | First twin (cephalic) | 1/6 | 2/6 | OR 0.59 (0.00–154.35) | 74 | Very low |
Second twin (non-cephalic) | 1/5 | 0/4 | OR 1.00 (0.02–40.28) | N/A | ||||
Both twins | 2/11 | 2/10 | OR 0.76 (0.03–17.34) | 48 |  | |||
Respiratory distress syndrome (RDS) | 25+0–27+6 | 2 | First twin (cephalic) | 13/14 | 15/15 | OR 0.23 (0.01–6.25) | N/A | Very low |
Second twin (non-cephalic) | 13/14 | 13/15 | OR 1.60 (0.12–20.99) | N/A | ||||
Both twins | 26/28 | 28/30 | OR 0.77 (0.10–5.87) | 0 |