Fig. 2

Composite outcome in a systematic review/meta-analyses on the safest mode of delivery for extremely preterm cephalic/non-cephalic twin pairs. SBI – Severe brain injury defined as intraventricular hemorrhage grade ≥3 or periventricular leukomalacia; IV – inverse variance; CI – confidence interval; I²-heterogeneity. Composite outcome consists of neonatal death or severe brain injury (SBI) in survivors, at 24⁰–27⁶ weeks’ gestation by mode of delivery