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Table 1 Transition in serum steroid hormone concentrations and follicular development during controlled ovarian stimulation

From: Successful pregnancy and live birth from a hypogonadotropic hypogonadism woman with low serum estradiol concentrations despite numerous oocyte maturations: a case report

First COS

 

MC day

MC Day 3

MC Day 8

MC Day 11

MC Day 13

 

(rFSH administration)

(0 IU)

(1125 IU)

(1800 IU)

(2250 IU)

 

E2

10a

219

484

 

(pg/ml)

 

LH

0.1a

0.1a

0.1a

 

(mIU/ml)

 

FSH

0.1

 

(mIU/ml)

 

P4

1.05

2.09

 

(ng/ml)

 

Follicular diameter (mm)

NM

6–8

9–12

15–19

 

Second COS

MC day

MC Day 3

MC Day 8

MC Day 10

MC Day 12

MC Day 15

(rFSH administration)

(0 IU)

(875 IU)

(1225 IU)

(1625 IU)

(2225 IU)

E2

10a

60

201

701

(pg/ml)

LH

0.1a

0.1a

0.1a

0.1a

(mIU/ml)

FSH

0.2

(mIU/ml)

P4

0.40

0.53

2.11

(ng/ml)

Follicular diameter (mm)

6–8

6–8

10

13–15

14–22

  1. Note: COS controlled ovarian stimulation, MC menstrual cycle, IU international units, NM not measurable, bar no data, E 2 estradiol, LH luteinizing hormone, FSH follicle stimulating hormone, P 4 progesterone
  2. aunder detection limit