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Fig. 2 | BMC Pregnancy and Childbirth

Fig. 2

From: Successful pregnancy and live birth from a hypogonadotropic hypogonadism woman with low serum estradiol concentrations despite numerous oocyte maturations: a case report

Fig. 2

Comparison of steroid hormone concentrations of this patient to those of infertile patients (Inf-), Inf-A and Inf-B. On day 4 of the menstrual cycle, these infertile women received daily administration of 100 mg clomifene citrate (CC) for 5 days. Follicular diameters were 25.2 mm and 18.1 mm for Inf-A and 22.8 mm for Inf-B on the day of induced ovulation. From the same day, serum hormone concentrations for Inf-A and Inf-B were 692 pg/ml and 745 pg/ml E2, 10.5 mIU/ml and 8.0 mIU/ml LH, and 0.40 ng/ml and 0.29 ng/ml P4, respectively. Ovulation was induced with 600 μg gonadotropin releasing hormone (GnRH) agonist, followed by oocyte pick-up (OPU), in vitro fertilization (IVF) and follicular fluids (FFs) cryopreservation in the same manner. However, no oocyte was collected from Inf-A, while one oocyte was collected from Inf-B, but its development ceased after fertilization. Although progesterone (P4), dehydroepiandrosterone sulfate (DHEA-S) and androstenedione (A2) concentrations in FFs of this patient did not differ from those of Inf-A and Inf-B, estrone (E1), testosterone (T) and estradiol (E2) concentrations were lower than those of Inf-A and Inf-B

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