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Table 4 Association of vitamin D supplementation and pregnancy-induced hypertension (PIH) outcomes in clinical trials

From: The role of vitamin D in pre-eclampsia: a systematic review

Author, Location, Year Study Design Subjects Intervention Key Findings Results
Olsen and Secher, Denmark, 1990 [91] Randomized controlled clinical trial 5644 pregnant women 2500 IU vitamin D supplement versus no supplement at week 20 of pregnancy ↓ PE 31.5% reduction in the odds (p < 0.005)
Olsen et al., Europe, 2000 [98] Randomized placebo controlled clinical trial 386 women who previously experienced PIH 2.7 g n-3 fatty acids/day given from 33 weeks until delivery vs olive oil placebo ↔ PIH recurrence risk OR = 0.98
95% CI: 0.63–1.53