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Table 2 Exposure-disease associations within the general Western Australian population and the Raine Study subsets. Data presented as odds ratio, 95% confidence interval, and p-value

From: The Raine study had no evidence of significant perinatal selection bias after two decades of follow up: a longitudinal pregnancy cohort study

 

Western Australia

Raine Pregnancy Cohort at birth

Raine 5-year Subset

Raine 20-year Subset

Raine Growth Subset

Raine NAFLD Subset

Vacuum extraction vs. neonatal jaundice

1.42

2.11

1.94

1.87

1.22

1.21

(1.25, 1.62)

(1.38, 3.23)

(1.15, 3.28)

(0.93, 3.77)

(0.54, 2.71)

(0.56, 2.58)

<0.001

<0.001

0.013

0.079

0.634

0.629

Low birth weight vs. spontaneous vaginal delivery

0.73

0.77

0.73

0.72

0.85

0.71

(0.71, 0.75)

(0.65, 0.91)

(0.59, 0.90)

(0.55, 0.93)

(0.65, 1.11)

(0.54, 0.93)

<0.001

0.002

0.003

0.014

0.234

0.014

Maternal age > 30y vs. elective caesarean section

1.87

1.89

2.07

2.89

1.92

2.51

(1.79, 1.95)

(1.48, 2.41)

(1.54, 2.77)

(1.91, 4.37)

(1.33, 2.78)

(1.66, 3.79)

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

Preterm birth vs. neonatal jaundice

4.30

4.58

7.48

8.98

9.84

7.88

(3.90, 4.73)

(3.59, 5.84)

(5.33, 10.51)

(5.55, 14.53)

(5.99, 16.16)

(4.90, 12.70)

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

Maternal smoking vs. low birth weight

NA

1.87

1.86

1.97

1.87

2.12

(1.51, 2.31)

(1.42, 2.44)

(1.39, 2.79)

(1.34, 2.62)

(1.48, 3.05)

<0.001

<0.001

<0.001

<0.001

<0.001

Pre-eclampsia vs. preterm birth

NA

1.89

1.64

2.04

1.76

1.81

(1.30, 2.73)

(1.20, 2.24)

(1.35, 3.09)

(1.68, 2.66)

(1.18, 2.76)

<0.001

0.002

<0.001

0.007

0.006