Table 2 Longitudinal variation of median serum fatty acids during pregnancy between fish oil (EPA and DHA) and control groups (T0, T1 and T2). (Intention-to-treat analysis)
Fatty acids (μg/mL) | Fish oil Supplement (n = 32) | Control (n = 28) | p-valuea |
|---|---|---|---|
Total n-6 | |||
T0 | 1018.3 (856.8–1159.9) | 939.7 (793.2–1047.7) | 0.076 |
T1 | 1274.8 (1098.0–1500.6) | 1252.9 (1109.3–1404.2) | 0.563 |
T2 | 1356.1 (1123.3–1551.3) | 1362.1 (1212.6–1553.9) | 0.678 |
Total n-3 | |||
T0 | 94.7 (78.4–110.6) | 95.1 (83.1–104.9) | 0.976 |
T1 | 112.6 (95.0–127.3) | 116.2 (105.0–132.2) | 0.524 |
T2 | 154.7 (109.6–194.2) | 121.1 (94.5–131.9) | 0.020 |
n-6/n-3 ratio | |||
T0 | 11.4 (10.3–12.2) | 10.3 (8.9–11.7) | 0.108 |
T1 | 11.7 (9.9–13.0) | 10.3 (9.7–12.4) | 0.328 |
T2 | 9.5 (7.0–11.9) | 11.6 (10.0–12.6) | 0.004 |
Eicosapentaenoic acid | |||
T0 | 9.2 (7.0–11.2) | 9.5 (6.5–12.3) | 0.903 |
T1 | 8.7 (6.8–10.7) | 8.5 (6.7–12.8) | 0.813 |
T2 | 11.9 (7.6–26.4) | 7.5 (4.3–11.0) | 0.005 |
Docosahexaenoic acid | |||
T0 | 56.8 (47.1–67.4) | 57.4 (48.9–68.3) | 0.844 |
T1 | 67.5 (61.6–81.0) | 75.5 (59.8–84.6) | 0.505 |
T2 | 97.1 (66.0–120.0) | 73.5 (62.8–83.9) | 0.021 |