Table 1 Baseline characteristics and the outcomes of the 578 women using serotonergic medication and the controls before and after matching
| Â | Before matching | After matching with 5 controls | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Women with SRmed | Controls (Perined) | Women with SRmed | Controls (Perined) | |||||||
(n = 578) | % | (n = 641,364) | % | p-value | (n = 578) | % | (n = 2890) | % | p-value | |
Characteristics | ||||||||||
 Nulliparity | 258 | 44.6% | 289,190 | 45.1% | NS | 258 | 44.6% | 1290 | 44.6% | NS |
 Caucasian ethnicity | 351 | 60.7% | 522,141 | 81.4% | <0.0001 | 351 | 60.7% | 1750 | 60.6% | NS |
 Low socioeconomic status | 286 | 49.5% | 155,183 | 24.2% | <0.0001 | 286 | 49.5% | 1429 | 49.4% | NS |
 Maternal age > = 35 years | 195 | 33.7% | 131,584 | 20.5% | <0.0001 | 195 | 33.7% | 971 | 33.6% | NS |
 Previous PPH | 16 | 2.8% | 6782 | 1.1% | <0.0001 | 16 | 2.8% | 80 | 2.8% | NS |
 Induction of labour | 135 | 23.4% | 135,251 | 21.1% | NS | 135 | 23.4% | 674 | 23.3% | NS |
 Hypertension | 47 | 8.1% | 52,763 | 8.2% | NS | 47 | 8.1% | 230 | 8.0% | NS |
 Macrosomia P90 | 59 | 10.2% | 65,522 | 10.2% | NS | 59 | 10.2% | 290 | 10.0% | NS |
 Gestational duration <37 weeks | 43 | 7.4% | 34,322 | 5.4% | 0.0258 | 43 | 7.4% | 216 | 7.5% | NS |
Outcome | ||||||||||
 PPH (>1000 ml) | 56 | 9.7% | 39,171 | 6.1% | 0.0003 | 56 | 9.7% | 191 | 6.6% | 0.009 |