Table 6 Summary of studies reporting incidence of influenza-associated deaths
From: Incidence of influenza virus infection among pregnant women: a systematic review
Study | Number of cases | Denominator | Crude incidence rate (CI) | 95% CI | Pandemic or seasonal? | Study design | Grading system and scoreb | Hospital-based or clinic-based? | Inclusion criteria | Duration of surveillance (months or years) | Country |
|---|---|---|---|---|---|---|---|---|---|---|---|
Jamieson 2009 | 1 | 3,392,060 | 0.003 per 10,000 pregnanciesa | (0.000–0.021) | Pandemic | Case series | JBI = 6/7 | Both | Pregnant women with laboratory-confirmed (PCR or culture) H1N1 | 1 month | US |
Creanga 2010 | 2 | 113,877 | 0.18 per 10,000 pregnancies | (0.04–0.70) | Pandemic | Case series | JBI = 6/7 | Hospital | Reproductive-aged women with rtPCR-confirmed H1N1 hospitalized in NYC | 2 months | US |
Knight 2011 | 6 4 | 86,449 193,796 | 0.69 per 10,000 pregnancies 0.21 per 10,000 pregnanciesb | (0.26–1.51) (0.06–0.53) | Pandemic | Case series | JBI = 6/7 | Hospital | Confirmed AH1N1v infection during pregnancy and subsequently admitted to ICU | 5 months 3 months | Australia/New Zealand UK |
Doyle 2013 | 8 | 295,941 | 0.27 per 10,000 pregnanciesa | (0.14–0.54) | Pandemic | Case series | NOS = 8 | Both | Acute respiratory illness, with laboratory confirmation of pH1N1 by a certified laboratory | 13 months | US |