Table 3 Neonatal outcome of 15 fetuses infected with Toxoplasma gondii, in relation to maternal serologic group
Year of AC | Serologic group | Time of detected infection | Gestational age at AC | PCR in amniotic fluid | Antiparasitic treatment | Ultrasound findings | Gestational age at birth | Birth weight | Findings after birth |
|---|---|---|---|---|---|---|---|---|---|
Trimester (weeks) | Weeks | Drugs | Weeks | Gram | |||||
1994 | Sc | 3 (29.1) | 31.0 | + | Sp, PS | – | 39.0 | 3830 | I.c. calcifications |
1995 | Sc | 2 (19.4) | 29.4 | + | PS | Small BPD | 30.3 | 1500 | I.c. calcifications, hydrocephaly, chorioretinitis |
1995 | Sc | 2 (26.6) | 35.6 | + | Az, PS | – | 40.9 | 3700 | Chorioretinitis |
1995 | Sc | 2 (27.0) | 29.3 | + | ? | ? | 31.4 | ? | |
1995 | Sc | 3 (33.9) | 36.3 | + | PS | – | 31.4 | No findings | |
1995 | Sc | 3 (36.3) | 37.7 | + | Az | – | 38.9 | 3880 | I.c. calcifications, parasites in placenta and CSF |
1999 | Sc | 3 (28.0) | 30.4 | + | Sp, PS | I.c. calcifications, splenomegaly | 41.9 | 3450 | Chorioretinitis, leptomeningeal changes on CT |
2000 | Sc | 3 (34.0) | 35.1 | + | Sp, PS | Splenomegaly, i.c. calcifications, renal pyelectasy | 37.4 | 3268 | I.c calcifications, operated because of atrial septal defect |
2000 | Sc | 3 (35.3) | 37.0 | + | PS | I.c. calcifications, splenomegaly | 42.1 | 3510 | No findings |
2002 | Sc | 2 (25.9) | 28.0 | + | Az, Sp, PS | – | 39.9 | 3650 | No findings |
2005 | Sc | 3 (35.3) | 37.7 | + | Az, Sp, PS | I.c. calcifications, splenomegaly | 38.3 | 3335 | Jaundice, reduced vision one eye |
1997 | Ti | 2 (14.7) | 17.0 | + | Sp | – | 17.7 | 204 | Termination. Parasites at autopsy; granulomas, paraventricular micronecrosis and T.gondii cysts in CNS. Lymphoid cells and macrocyts in lungs, necrosis and cysts in placenta |
1999 | Ti | 1 (8.6) | 13.7 | + | Az | Enlarged nuchal translucency | 15.4 | 44 | Planned termination but spontaneous fetal death. Parasites at autopsy found in CNS, lungs, liver and placenta. T.gondii cysts in lungs and placenta |
1993 | IgM+/IgGav | 1 (11.7) | 16.4 | + | Sp | – | 40.6 | 3695 | No findings |
2001 | IgM+/IgGav | 2 (17.6) | 20.4 | – | Az | – | 40.0 | IgM, PCR of placenta and umbilical cord blood positive at birth, IgA increase after 6 months and IgG increase first year of life |