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Table 5 Negative impact of NVP on daily life functioning and willingness to get pregnant again

From: The burden of nausea and vomiting during pregnancy: severe impacts on quality of life, daily life functioning and willingness to become pregnant again – results from a cross-sectional study

  PUQE
Totalb Mild Moderate Severe p-valuea
  N = 712 n (%) N = 62 n (%) N = 439 n (%) N = 210 n (%)  
1. Taking care of household chores
 No impact 29 (4.1) 14 (22.6) 14 (3.2) 1 (0.5) <0.001
 Minor impact 150 (21.1) 37 (59.7) 103 (23.5) 10 (4.8)  
 Major impact 533 (74.9) 11 (17.7) 322 (73.3) 199 (94.8)  
2. Social life
 No impact 44 (6.2) 18 (29.0) 23 (5.2) 3 (1.4) <0.001
 Minor impact 155 (21.8) 34 (54.8) 103 (23.5) 17 (8.1)  
 Major impact 513 (72.1) 10 (16.1) 313 (71.3) 190 (90.5)  
3. Relationship with partner c, n=682
 No impact 134 (19.6) 23 (38.3) 77 (18.2) 34 (17.1) <0.001
 Minor impact 306 (44.9) 32 (53.3) 193 (45.7) 80 (40.2)  
 Major impact 242 (35.5) 5 (8.3) 152 (36.0) 85 (42.7)  
4. Ability to care for children d, n=351
 No impact 31 (8.8) 10 (32.3) 16 (7.7) 5 (4.5) <0.001
 Minor impact 97 (27.6) 17 (54.8) 67 (32.2) 13 (11.6)  
 Major impact 223 (63.5) 4 (12.9) 125 (60.1) 94 (83.9)  
5. Work capacity e, n=671
 No impact 28 (4.2) 8 (13.8) 20 (4.9) 0 (0.0) <0.001
 Minor impact 147 (21.9) 40 (69.0) 95 (23.2) 12 (5.9)  
 Major impact 496 (73.9) 10 (17.2) 294 (71.9) 191 (94.1)  
6. Sick leave due to NVP f, n=649
 No 221 (34.1) 50 (84.7) 153 (38.8) 18 (9.2) <0.001
 Yes 428 (65.9) 9 (15.3) 241 (61.2) 178 (90.8)  
7. Considered to terminate the pregnancy due to NVP
 No 608 (85.5) 62 (100.0) 393 (89.5) 153 (72.9) <0.001
 Yes 100 (14.1) 0 (0.0) 44 (10.0) 56 (26.7)  
 Unsure 3 (0.4) 0 (0.0) 2 (0.5) 1 (0.5)  
8. Consider not to get pregnant again
 No 333 (46.8) 54 (87.1) 233 (53.1) 46 (21.9) <0.001
 Yes 353 (49.6) 6 (9.7) 188 (42.8) 159 (75.7)  
 Unsure 25 (3.5) 2 (3.2) 18 (4.1) 5 (2.4)  
  1. Abbreviations: CI, confidence interval; PUQE, 24 h Pregnancy-Unique Quantification of Emesis; NVP, nausea and vomiting of pregnancy
  2. aChi-square test or Fisher’s exact test when expected count were less than 5. Bold p-values indicate statistically significant differences between the groups
  3. bThe sums do not always add up to total due to missing (“not relevant”)
  4. c3.8% responded “not relevant”
  5. d52.3% did not have any children
  6. e6.8% responded “not relevant”
  7. f8.8% responded “not relevant”