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Table 3 NICU outcomes of very preterm singletons by mode of conceptions

From: Morbidity and mortality among very preterm singletons following fertility treatment in Australia and New Zealand, a population cohort study

  Number Percent OR (95% CI) AOR (95% CI)a
Hyaline membrane disease
 Spontaneous conception 14574 71.9 Ref Ref
 HO 154 72.0 1.00 (0.74–1.36) 0.87 (0.62–1.21)
 ART 724 76.9 1.30 (1.11–1.52) 1.18 (0.99–1.40)
 AI 38 72.1 0.93 (0.52–1.67) 0.75 (0.41–1.42)
Necrotizing enterocolitis
 Spontaneous conception 817 4.0 Ref Ref
 HO 3 1.4 0.34 (0.11–1.04) 0.33 (0.10–1.05)
 ART 49 5.2 1.30 (0.97–1.75) 1.43 (1.04–1.97)
 AI 2 3.7 0.92 (0.22–3.80) 0.85 (0.20–3.60)
Intra ventricular haemorrhage
 Spontaneous conception 4327 23.1 Ref Ref
 HO 53 26.0 1.17 (0.85–1.60) 1.23 (0.86–1.75)
 ART 229 25.6 1.14 (0.98–1.33) 1.20 (1.00–1.43)
 AI 12 23.1 0.99 (0.52–1.90) 1.21 (0.61–2.40)
Retinopathy of prematurity
 Spontaneous conception 3896 26.6 Ref Ref
 HO 49 31.6 1.27 (0.91–1.79) 1.04 (0.70–1.52)
 ART 187 27.2 1.03 (0.87–1.22) 1.00 (0.82–1.24)
 AI and other 10 23.3 0.83 (0.41–1.70) 0.99 (0.44–2.17)
Major surgery
 Spontaneous conception 1642 8.1 Ref Ref
 HO 23 10.7 1.37 (0.89–2.11) 1.27 (0.79–2.02)
 ART 122 12.9 1.70 (1.39–2.06) 1.71 (1.37–2.13)
 AI 6 11.1 1.43 (0.61–2.34) 1.00 (0.389–2.60)
Deaths
 Spontaneous conception 1852 9.0 Ref Ref
 HO 20 9.3 1.02 (0.65–1.63) 0.67 (0.38–1.18)
 ART 98 10.3 1.15 (0.93–1.43) 1.11 (0.86–1.42)
 AI 9 16.7 2.01 (0.98–4.13) 2.10 (0.93–4.76)
  1. a Adjusted for maternal age, gestational age, ethnicity, previous pre term, previous prenatal death, maternal hypertension, antepartum haemorrhage, premature rupture of membranes and antenatal steroid
  2. Significant results are in bold