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Table 1 Subject demography information

From: Subgroup identification of early preterm birth (ePTB): informing a future prospective enrichment clinical trial design

Variable

Newborn Gestational Age

< 34 weeks: ePTB

≥ 34 weeks

N = 134009

N = 3860863

Mothers’ Age (%)

≤ 24 Years

40711 (30.38)

1094793 (28.36)

 25-29 Years

34831 (25.99)

1112643 (28.82)

 30-34 Years

33578 (25.06)

1049775 (27.19)

  ≥ 35 Years

24889 (18.57)

603652 (15.64)

Mothers’ Nativity (%)

 Born in U.S.

107578 (80.28)

2996531 (77.61)

 Born Outside U.S. /Unknown/Not Stated

26431 (19.72)

864332 (22.39)

Mothers’ Race (%)

 White

88185 (65.81)

2938466 (76.11)

 Black

36554 (27.28)

603921 (15.64)

 American Indian/Alaskan Native/Asian or Pacific Islander

9270 (6.92)

318476 (8.25)

Mothers’ Hispanic Origin (%)

 Non-Hispanic/Hispanic Origin Not Stated

105011 (78.36)

2968422 (76.88)

 Hispanic

28998 (21.64)

892441 (23.12)

Marital Status (%)

 Married

65594 (48.95)

2323620 (60.18)

 Unmarried

68415 (51.05)

1537243 (39.82)

Mothers’ Education (%)

  ≤ High School or GED/Unknown

62819 (46.88)

1512489 (39.17)

 Associate/Some College Credit

37338 (27.86)

1086153 (28.13)

  ≥ Bachelor's

29145 (21.75)

1124077 (29.11)

 Missing

4707 (3.51)

138144 (3.58)

Pre-pregnancy Smoking Status (%)

 Nonsmoker

108663 (81.09)

3258557 (84.40)

 Smoker/Unknown/Not Stated

20639 (15.40)

464162 (12.02)

 Missing

4707 (3.51)

138144 (3.58)

Pre-pregnancy BMI (%)

 Under Weight-Normal ≤ 24.9

55824 (41.66)

1785913 (46.26)

 Overweight 25.0-29.9

30288 (22.60)

918380 (23.79)

 Obesity ≥ 30.0/Unknown/Not Stated

43190 (32.23)

1018426 (26.38)

 Missing

4707 (3.51)

138144 (3.58)

Pre-pregnancy Diabetes Status (%)

 No/Unknown/Not Stated

126901 (94.70)

3694967 (95.70)

 Yes

2401 (1.79)

27752 (0.72)

 Missing

4707 (3.51)

138144 (3.58)

Pre-pregnancy Hypertension Status (%)

 No/Unknown/Not Stated

123932 (92.48)

3667289 (94.99)

 Yes

5370 (4.01)

55430 (1.44)

 Missing

4707 (3.51)

138144 (3.58)

Previous Preterm Birth Status (%)

 No/Unknown/Not Stated

118468 (88.40)

3626879 (93.94)

 Yes

10834 (8.08)

95840 (2.48)

 Missing

4707 (3.51)

138144 (3.58)

Infertility Treatment Usage Status (%)

 No/Unknown/Not Stated

122859 (91.68)

3669850 (95.05)

 Yes

6443 (4.81)

52869 (1.37)

 Missing

4707 (3.51)

138144 (3.58)

Fertility Enhancing Drug Usage Status (%)

 No/Not Applicable/Unknown/Not Stated

126582 (94.46)

3697856 (95.78)

 Yes

2720 (2.03)

24863 (0.64)

 Missing

4707 (3.51)

138144 (3.58)

Delivery Payment Source (%)

 Medicaid

65048 (48.54)

1598851 (41.41)

 Private Insurance

51753 (38.62)

1771814 (45.89)

 Self-pay/Other/Unknown

12501 (9.33)

352054 (9.12)

 Missing

4707 (3.51)

138144 (3.58)