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Table 2 Comparison of base-line characteristics between mother-infant dyads whereby the final intervention was performed within 48 h and after 48 h postpartum

From: Use of antidepressants during pregnancy in the Netherlands: observational study into postpartum interventions

Variables

Intervention

<48 h

n = 60

Intervention

>48 h

n = 20

 

p-value

 

Mean (standard deviation)

 

Maternal age during delivery (years)

33.3 (4.7)

31.9 (4.3)

 

0.24

 

Median (interquartile range)

 

Duration of observation mother (days)

4 (3–5)

4 (3.3–5)

 

0.68

Duration of observation infant (days)

4 (3–5)

4 (3.3–5)

 

0.79

 

n (%)

Odds ratio

95% CI

 

Marital status

   

0.26*

 Single

6 (60.0)

4 (40.0)

1 (ref)

 

 Married/living together/LATa

54 (77.1)

16 (22.9)

0.44

0.11–1.77

Smoking

   

1.00*

 No

55 (76.4)

17 (23.6)

1 (ref)

 

 Yes

5 (83.3)

1 (16.7)

0.65

0.07–5.93

 Unknown

0

2

 

Type of psychotropic medication

   

1.00*

 Solely antidepressant

54 (75.0)

18 (25.0)

1 (ref)

 

 Antidepressant and other type of psychotropic drug

6 (75.0)

2 (25.0)

1.00

0.19–5.40

Dosage

   

0.19

 Minimal or below minimal effective daily

dosage

25 (83.3)

5 (16.7)

1 (ref)

 

 Above minimal effective daily dosage

35 (70.0)

15 (30.0)

0.47

0.15–0.69

Parity

   

0.16

 Primiparous

32 (82.1)

7 (17.9)

1 (ref)

 

 Multiparous

28 (68.3)

13 (31.7)

2.12

0.74–6.06

HADSb

    

 Anxiety scale not elevated

27 (73.0)

10 (27.0)

1 (ref)

0.74

 Anxiety scale elevated

32 (76.2)

10 (23.8)

0.84

0.31–2.33

 

 Depression scale not elevated

32 (74.4)

11 (25.6)

1 (ref)

0.95

 Depression scale elevated

27 (75.0)

9 (25.0)

0.97

0.35–2.69

 

 No scales elevated

24 (75.0)

8 (25.0)

1 (ref)

0.96

 One or both scales elevated

35 (74.5)

12 (25.5)

1.03

0.37–2.89

 

 Unknown

1

0

 

Gender infant

   

0.60

 Male

32 (72.7)

12 (27.3)

1 (ref)

 

 Female

28 (77.8)

8 (22.2)

0.76

0.27–2.13

Type of birth

   

0.66

 Vaginal

45 (76.3)

14 (23.7)

1 (ref)

 

 Caesarean Section

15 (71.4)

6 (28.6)

1.29

0.42–3.94

Type of feeding

   

0.67

 Breastfeeding or mixed feeding

42 (73.7)

15 (26.3)

1 (ref)

 

 Exclusively formula

18 (78.2)

5 (21.7)

0.78

0.25–2.46

Gestational age

   

0.57*

  < 37 weeks

4 (100.0)

0 (0.0)

Not possible to calculate

 

  ≥ 37 weeks

56 (73.7)

20 (26.3)

Finnegan score, highest during observation

   

0.50*

  < 4

12 (85.7)

2 (14.3)

1 (ref)

 

  ≥ 4

48 (72.7)

18 (27.3)

2.25

0.46–11.06

  1. Odds ratios and 95% confidence intervals are presented
  2. *Calculated with Fisher exact test
  3. aLAT: Living apart together
  4. bHADS: Hospital anxiety and depression scale