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Table 1 Baseline characteristics of pregnant women participating in our cohort by HG exposure status

From: Hyperemesis gravidarum and placental dysfunction disorders

 

HG exposure

P

No HG (n = 1833)

Mild HG (n = 354)

Severe HG (n = 46)

Demographic characteristics

Age (years) Median (IQR)

28.09 (8.7)

28.13 (7.4)

28.36 (9.1)

0.62

Women’s educationa

0.15

 Low

413 (22.6)

73 (20.6)

10 (22.2)

 Intermediate

1123 (61.4)

208 (58.8)

31 (68.9)

 High

292 (16.0)

73 (20.6)

4 (8.9)

Partner’s educationa

0.23

 Low

323 (17.7)

46 (13.0)

9 (20.0)

 Intermediate

1199 (65.6)

241 (68.1)

30 (66.7)

 High

305 (16.7)

67 (18.9)

6 (13.3)

Family incomeb

   

0.01*

  < 72 USD

197 (10.8)

26 (7.3)

5 (10.9)

 72–180 USD

799 (43.6)

169 (47.7)

18 (39.1)

 180–360 USD

529 (28.9)

126 (35.6)

16 (34.8)

  > 360 USD

124 (6.8)

17 (4.8)

3 (6.5)

 Refused to answer

182 (9.9)

16 (4.5)

4 (8.7)

Health characteristics

Pre-pregnancy BMI Median (IQR)

22.0 (5.5)

22.2 (5.5)

23.2 (6.6)

0.59

Chronic hypertension

27 (1.5)

5 (1.4)

0

0.71

Type 2 diabetes

11 (0.6)

2 (0.6)

0

0.87

Partner’s smoking status

0.12

 Smokes daily

394 (48.6)

70 (50.7)

8 (36.4)

 Smokes occasionally

113 (13.9)

12 (8.7)

1 (4.5)

 Doesn’t smoke

304 (37.5)

56 (40.6)

13 (59.1)

Obstetrics characteristics

Primigravida

480 (38.0)

112 (41.5)

12 (34.3)

0.50

Gestational age (weeks) at first visit Median (IQR)

16 (20)

9 (4.50)

10 (5.0)

0.00*

Reported complications in previous pregnancy

 

 No

1070 (84.6)

233 (86.0)

29 (82.9)

0.80

 IUGR/SGA

3 (0.2)

0

0

0.70

 Hypertensive disorder in pregnancy

44 (2.4)

11 (3.1)

1 (2.2)

0.74

 Miscarriage

136 (7.4)

28 (7.9)

2 (4.3)

0.69

Female baby

651 (46)

133 (46.5)

22 (59.5)

0.27

Multiple pregnancy

27 (1.9)

1 (0.4)

0

0.12

Mode of delivery

0.08

 Vaginal

871 (61.3)

168 (58.9)

24 (64.9)

 Instrumental

33 (3.1)

11 (3.9)

4 (10.8)

 Caesarean section

506 (35.6)

106 (37.2)

9 (24.3)

  1. Abbreviations: HG Hyperemesis gravidarum, USD United States Dollar, IUGR intra uterine growth restriction, SGA small for gestational age, IQR inter-quartile range. Results are median (inter-quartile range) or numbers (percentage); For continuous outcome variables Kruskall-Wallis test was used, for categorical variables, Pearson’s chi-square test
  2. aLow education = no education, elementary school, junior high school; Intermediate education = senior high school or above; High education = university
  3. bMean monthly total family income, estimated by the patient
  4. *P <0,05