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Table 1 Phenotype of the study population (healthy pregnant women participating in the longitudinal arm of the study and women participating in the cross-sectional arm of the study who developed preeclampsia). Continuous variables are presented as mean ± SE or median (range) and categorical variables as n (%) as appropriate. Doppler ultrasonography was performed at 22–24 weeks of gestation

From: Longitudinal reference ranges for maternal plasma laeverin, and its role as a potential biomarker of preeclampsia

  Longitudinal study Women who developed preeclampsia P value
Healthy women (n = 53) Preeclampsia (n = 15)
Maternal age, median (range), years 28.7 (18–39) 27.5 (18–40) 0.368
Body mass index before delivery, (kg/m2) 25.11 ± 0.41 25.75 ± 1.08 0.504
Primipara, n (%) 36 (68) 8 (53.3) 0.304
Mean arterial pressure, mmHg 79.40 ± 3.12 87.55 ± 1.28 0.003
Uterine artery pulsatility index (mean of the left and right side) 0.80 ± 0.02 1.24 ± 0.04 0.000
Middle cerebral artery pulsatility index 1.62 ± 0.06 1.82 ± 0.05 0.070
Umbilical artery pulsatility index 0.80 ± 0.02 1.24 ± 0.04 0.000
Gestational age at delivery, median (range), weeks 40 (37–42) 39 (32–41) 0.849
Cesarean section, n (%) 3 (5.66) 2 (13.33) 0.322
Neonatal birth weight, g 3562 ± 65 3329 ± 163 0.122
Placental weight, g 591 ± 17 584 ± 22 0.833
5 min APGAR score median (range) 10 (7–10) 9 (6–10) 0.472
Arterial cord blood pH 7.24 ± 0.02 7.23 ± 0.03 0.829
Arterial cord blood Base Excess, mmol/L −5.65 ± 0.62 −3.59 ± 1.45 0.164
Venous cord blood pH 7.36 ± 0.01 7.35 ± 0.02 0.816
Venous cord blood Base Excess, mmol/L −4.50 ± 0.45 −4.11 ± 1.35 0.731