Table 1 Phenotype of the study population (healthy pregnant women participating in the longitudinal arm of the study and women participating in the cross-sectional arm of the study who developed preeclampsia). Continuous variables are presented as mean ± SE or median (range) and categorical variables as n (%) as appropriate. Doppler ultrasonography was performed at 22–24 weeks of gestation
Longitudinal study | Women who developed preeclampsia | P value | |
|---|---|---|---|
Healthy women (n = 53) | Preeclampsia (n = 15) | ||
Maternal age, median (range), years | 28.7 (18–39) | 27.5 (18–40) | 0.368 |
Body mass index before delivery, (kg/m2) | 25.11 ± 0.41 | 25.75 ± 1.08 | 0.504 |
Primipara, n (%) | 36 (68) | 8 (53.3) | 0.304 |
Mean arterial pressure, mmHg | 79.40 ± 3.12 | 87.55 ± 1.28 | 0.003 |
Uterine artery pulsatility index (mean of the left and right side) | 0.80 ± 0.02 | 1.24 ± 0.04 | 0.000 |
Middle cerebral artery pulsatility index | 1.62 ± 0.06 | 1.82 ± 0.05 | 0.070 |
Umbilical artery pulsatility index | 0.80 ± 0.02 | 1.24 ± 0.04 | 0.000 |
Gestational age at delivery, median (range), weeks | 40 (37–42) | 39 (32–41) | 0.849 |
Cesarean section, n (%) | 3 (5.66) | 2 (13.33) | 0.322 |
Neonatal birth weight, g | 3562 ± 65 | 3329 ± 163 | 0.122 |
Placental weight, g | 591 ± 17 | 584 ± 22 | 0.833 |
5 min APGAR score median (range) | 10 (7–10) | 9 (6–10) | 0.472 |
Arterial cord blood pH | 7.24 ± 0.02 | 7.23 ± 0.03 | 0.829 |
Arterial cord blood Base Excess, mmol/L | −5.65 ± 0.62 | −3.59 ± 1.45 | 0.164 |
Venous cord blood pH | 7.36 ± 0.01 | 7.35 ± 0.02 | 0.816 |
Venous cord blood Base Excess, mmol/L | −4.50 ± 0.45 | −4.11 ± 1.35 | 0.731 |