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Table 4 Tocolysis regression results

From: Impact of obstetric interventions on condition at birth in extremely preterm babies: evidence from a national cohort study

Model

 

Complete population

Steroids-only population

  

N

OR

95% CI

P-valuea

N

OR

95% CI

P-valuea

Condition at birth

        
 

Baseline

1720

2.25

(1.75 – 2.90)

<0.0001

1213

1.44

(1.08 – 1.95)

0.0138

 

Baseline + GAb

1720

1.64

(1.24 – 2.18)

<0.0001

1213

1.53

(1.12 – 2.09)

<0.0001

 

Clinicalc

1655

1.37

(1.01 – 1.87)

<0.0001

1205

1.42

(1.04 – 1.96)

<0.0001

 

Counsellingd

1655

1.45

(1.05 – 2.00)

<0.0001

1205

1.47

(1.06 – 2.04)

<0.0001

Delivery Room death

        
 

Baseline

1720

0.33

(0.24 – 0.44)

<0.0001

1213

0.53

(0.36 – 0.76)

0.0005

 

Baseline + GAb

1720

0.46

(0.32 – 0.65)

<0.0001

1213

0.47

(0.31 – 0.70)

<0.0001

 

Clinicalc

1655

0.58

(0.39 – 0.84)

<0.0001

1211

0.49

(0.32 – 0.73)

<0.0001

 

Counsellingd

1655

0.48

(0.32 – 0.73)

<0.0001

1211

0.43

(0.28 – 0.66)

<0.0001

  1. Odds ratios of the effect of tocolysis on the presence of a heart rate greater than 100 at minutes of age or to delivery room death in the complete population of babies born at 22–26 completed weeks of gestation in England in 2006 who were known to be alive at admission to hospital and at the start of labour monitoring or delivery to perform Caesarean section, and the restricted population of those babies born to women who received antenatal steroids
  2. aLikelihood ratio test p-value comparing model against next simplest model
  3. bGA: gestational age
  4. cThe clinical models for condition at birth and delivery room death were adjusted for: provision of antenatal steroids, NICU level at birth, in utero transfer and presence of placental abruption
  5. dIn addition to the factors adjusted for in the clinical models, the complete models were also adjusted for who counselling was provided by, whether and what choice was expressed for resuscitation, and whether a decision was made to not perform Caesarean section in the presence of fetal distress