Skip to main content

Table 1 Characteristics of key variables for the different study populations used in the obstetric antecedents investigation

From: Impact of obstetric interventions on condition at birth in extremely preterm babies: evidence from a national cohort study

Variable   “Complete” population ‘Counselled’ population “Steroids only” population
   N % N % P-valuea N % P-valueb
Antenatal steroids 1701 1484 1213
  None 488 28.69 358 24.12 0.01 0 0.00 <0.01
  Partial 452 26.57 400 26.95   452 37.26  
  Full 761 44.74 726 48.92   761 62.74  
Tocolysis 1720 1495 1213
  No 1283 74.59 1085 72.58 0.21 807 66.53 <0.01
  Yes 437 25.41 410 27.42   406 33.47  
Delivery mode 1717 1495 1213
  Vaginal 1361 79.27 1170 78.26 0.51 901 74.28 <0.01
  Caesarean 356 20.73 325 21.74   312 25.72  
Gestational age 1722 1495 1213
  22 weeks 204 11.85 165 11.04 0.90 19 1.57 <0.01
  23 weeks 281 16.32 252 16.86   139 11.46  
  24 weeks 366 21.25 322 21.54   303 24.98  
  25 weeks 436 25.32 391 26.15   374 30.83  
  26 weeks 435 25.26 365 24.41   378 31.16  
Fetal sex 1719 1492 1213
  Female 804 46.77 699 46.85 0.99 586 48.31 0.43
  Male 915 53.23 793 53.15   627 51.69  
HR >100 5 min after birth 1722 1495 1213
  No 600 34.84 505 33.78 0.55 274 22.59 <0.01
  Yes 1122 65.16 990 66.22   939 77.41  
Delivery room death 1722 1495 1213
  No 1238 71.89 1078 72.11 0.92 1035 85.33 <0.01
  Yes 484 28.11 417 27.89   178 14.67  
Counselled by... 1722 1495 1213
  No one/not counselled 227 13.18 0 0.00 <0.01 87 7.17 <0.01
  Junior obstetrician only 168 9.76 168 11.24   94 7.75  
  Senior obstetrician only 165 9.58 165 11.04   96 7.91  
  Paediatrician and junior obstetrician 418 24.27 418 27.96   353 29.10  
  Paediatrician and senior obstetrician 744 43.21 744 49.77   583 48.06  
Decision to not perform C/S 1158 1017 820
  No 807 69.69 666 65.49 0.04 571 69.63 1.00
  Yes 351 30.31 351 34.51   249 30.37  
Resuscitation choice expressed 1235 1130 881
  No choice expressed 508 41.13 403 35.66 0.06 332 37.68 <0.01
  Full intensive care 391 31.66 391 34.60   346 39.27  
  Withhold intensive care 45 3.64 45 3.98   9 1.02  
  At paediatric discretion 291 23.56 291 25.75   194 22.02  
Discussion about withholding care 1178 1048 816
  Not discussed 713 60.53 583 55.63 0.02 545 66.79 0.01
  Discussed 465 39.47 465 44.37   271 33.21  
  1. Characteristics of key variables from the EPICure 2 cohort study of births at 22–26 completed weeks of gestation in England in 2005. Mother-baby pairs were divided into three populations: the full population consisted of babies who were alive at admission to hospital and the commencement of labour monitoring or the decision to perform caesarean section (C/S). The two sub-populations studied in sensitivity analyses comprised mothers who received counselling, and those who received steroids
  2. aChi-squared test comparing distributions in the “counselled” and “full” populations
  3. bChi-squared test comparing distributions in the “steroids only” and “full” populations