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Table 2 Gestational age and CYFRA 21–1 serum levels at the seven sample collection time points during pregnancy

From: The usefulness of CYFRA 21–1 to diagnose and predict preeclampsia: a nested case-control study

visit   Control PE_long PE_state Total
1 n 50 8 0 58
GA 12.14 (11.75–12.68) 12.43 (12.32–13.04)   12.14 (11.86–12.71)
CYFRA 2.35 (2.1–2.77) 1.75 (1.48–2.15)   2.3 (1.9–2.7)
2 n 47 9 0 56
GA 16.14 (15.36–16.79) 16.57 (16.14–17)   16.29 (15.43–16.86)
CYFRA 2.2 (1.8–2.6) 2.1 (1.8–2.6)   2.15 (1.8–2.6)
3 n 50 9 1 60
GA 20.57 (20.32–21) 20.57 (20.14–20.86) 22.86 (22.86–22.86) 20.57 (20.25–21)
CYFRA 1.9 (1.52–2.4) 2 (1.7–2.5) 3 (3–3) 1.9 (1.58–2.42)
4 n 47 8 12 67
GA 25.14 (24.71–25.93) 24.79 (24.21–25.36) 25.5 (24.96–26.93) 25 (24.71–26.07)
CYFRA 2 (1.65–2.55) 2.35 (2.18–3.43) 3.8 (2.82–4.12) 2.3 (1.85–2.9)
5 n 45 7 13 65
GA 30 (28.86–31.14) 29 (28.93–30.71) 30.14 (28.57–31.71) 30 (28.71–31.29)
CYFRA 2.3 (1.9–2.9) 2.6 (2.45–3.4) 4.7 (3.9–5.5) 2.6 (2.1–3.9)
6 n 47 6 19 72
GA 34 (33.29–35.29) 33.36 (33.07–33.64) 34.86 (33.71–35.5) 34 (33.39–35.43)
CYFRA 3.2 (2.5–3.8) 3.8 (3.3–5.12) 6 (4.55–6.85) 3.65 (2.85–5.58)
7 n 31 1 5 37
GA 37.57 (37–38.14) 37.86 (37.86–37.86) 37.29 (37–37.29) 37.43 (37–38.14)
CYFRA 3.7 (2.9–4.35) 4.3 (4.3–4.3) 4 (3.7–4.5) 3.8 (3–4.5)
  1. GA and CYFRA values are presented as the median (interquartile range)
  2. GA gestational age in weeks, CYFRA serum CYFRA 21–1 levels in ng/ml