Benefits and harms of screening for and treatment of asymptomatic bacteriuria in pregnancy: a systematic review

Table 5 Sensitivity analysis

Outcome measure	Treatment group		Control group		Difference between groups
Study	N	Events (%)	N	Events (%)	OR [95 % CI]; p-value
Pyelonephritis
Williams [22] Sensitivity analysis I	106^a	5 (5)	105^a	18 (17)	0.24^b [0.19–1.05]^b; 0.004^c
Williams [22] Sensitivity analysis II	106^a	9 (8)^d	105^a	18 (17)	0.45^b [0.19–1.05]^b; 0.066^c

CI confidence interval, CSZ convexity, symmetry, z score, OR odds ratio
^aIQWiG’s own calculation: all participants included (211 instead of the 163 actually analysed); both the treatment and control group were of equal size
^bIQWiG’s own calculation
^cIQWiG’s own calculation, unconditioned exact test (CSZ method as described in [25])
^dThe level of significance would not be missed until at least four additional events occurred in the treatment group while no additional events occurred in the control group (assumption)

ISSN: 1471-2393