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Table 4 Outcome measurements of each study

From: The influence of physical activity during pregnancy on maternal, fetal or infant heart rate variability: a systematic review

First author, year

Type of analyses

VLF (ms2)

LF (ms2)

HF (ms2)

IntF (ms2)

May, [47]

Difference in maternal HRV between exercise and control group at gw28, gw32, and gw36

maternal

gw28:

exercise: 1082.6 ± 1135.6

control: 558.9 ± 392.0 (p = 0.03)

maternal

gw28:

exercise: 436.8 ± 614.0

control: 263.7 ± 213.0 (n.s.)

maternal

gw28:

exercise: 1402.3 ± 2990.0

contro:l 431.1 ± 395.4 (n.s.)

---

gw32:

exercise: 1237.2 ± 942.5

control: 669.1 ± 513.1 (p = 0.008)

gw32:

exercise: 377.2 ± 473.7

control: 186.3 ± 135.9 (p = 0.05)d

gw32:

exercise: 911.2 ± 1334.8

control: 363.5 ± 365.0 (p = 0.048)

gw36:

exercise: 1529.4 ± 1325.8

control: 1097.2 ± 701.9 (n.s.)

gw36:

exercise: 368.6 ± 394.1

control: 201.2 ± 163.3 (n.s.)

gw36:

exercise: 805.6 ± 1165.5

control: 322.4 ± 387.4 (n.s.)

Van Leeuwen, [41]

Difference in maternal and fetal HRV between exercise and control group

---

---

---

---

May, Suminski, [37]

Correlation between continuous and non-continuous maternal LTPA and fetal HRV

fetal

continuous LTPA

R = 0.45 (p < 0.005)

fetal

continuous LTPA

R = 0.34 (p < 0.05)

fetal

continuous LTPA

R = 0.4 (p < 0.05)

---

non-continuous LTPA

R = 0.06 (n.s.)

non-continuous LTPA

R = 0.29 (n.s.)

non-continuous LTPA

R = 0.03 (n.s.)

May, Scholtz, [39]

Difference in infant HRV between exercise and control group

---

infanta

exercise: 2.38 ± 0.2

control: 2.06 ± 0.36 (p = 0.002)

infanta

exercise: 1.72 ± 0.27

control: 1.38 ± 0.39 (p = 0.004)

---

Gustafson, [42]

Difference in fetal HRV between exercise and control group adjusted for fetal breathing

fetala

estimate: 1.25; SE: 0.45

(n.s.)

fetala

estimate: 1.01 SE: 0.46

(n.s.)

fetala

estimate: 0.81; SE: 0.25

(p = 0.03)

fetala

estimate: 1.22; SE: 0.42 (p = 0.03)

May, [38]

Correlation between maternal LTPA (intensity, duration) and fetal HRV

Regression to predict fetal heart measures

fetal

intensityb

R = 0.29 (p < 0.05)

fetal

intensityb

R = 0.20 (n.s.)

fetal

intensityb

R = 0.24 (n.s.)

fetal

intensityb

R = 0.27 (n.s.)

durationc

R = 0.34 (p < 0.05)

durationc

R = 0.32 (p < 0.05)

durationc

R = 0.38 (p < 0.01)

durationc

R = 0.32 (p < 0.05)

positively predicted by duration (p = 0.007)

positively predicted by duration (p = 0.014)

positively predicted by duration (p = 0.003)

---

Stutzman [43]

Within and between group changes from pre (gw20) to post (gw36) for each of the four groups; results are only presented for the HRV outcomes measured in supine position

---

maternal

exercise – NW:

gw20: 194.4 ± 242

gw36: 116.2 ± 148 (n.s.)

maternal

exercise – NW:

gw20: 278.9 ± 504

gw36: 290.8 ± 606 (n.s.)

---

exercise – OaO:

gw20: 126.6 ± 143.7

gw36: 37.8 ± 15 (n.s.)

exercise – OaO:

gw20: 101.1 ± 99.7

gw36: 25.4 ± 23.8 (n.s.)

control – NW:

gw20: 184.2 ± 176

gw36: 83.4 ± 76 (sig.)*

control – NW:

gw20: 361.9 ± 370

gw36: 111.8 ± 161 (n.s.)

control – OaO:

gw20: 141.1 ± 181

gw36: 107.5 ± 202.1 (sig.)*

control – OaO:

gw20: 376.1 ± 723

gw36: 122.2 ± 265.7 (n.s.)

May, [40]

Changes in fetal HRV between exercise and control groups depending on fetal state (active vs. passive) at gw28, gw32, and gw36

fetala,e

gw28:

exercise: 4.2 ± 0.5

control 3.9 ± 0.5 (n.s.)

fetala,e

gw28:

exercise: 4.2 ± 0.5

control 3.9 ± 0.5 (n.s.)

fetala,e

gw28:

exercise: 2.2 ± 0.5

control 1.8 ± 0.5 (n.s.)

fetala,e

gw28:

exercise: 2.3 ± 0.6

control 1.7 ± 0.9 (n.s.)

gw32:

exercise: 4.6 ± 0.6

control: 4.1 ± 0.5 (n.s.)

gw32:

exercise: 4.6 ± 0.6

control: 4.1 ± 0.5 (n.s.)

gw32:

exercise: 2.2 ± 0.6

control: 1.9 ± 0.5 (n.s.)

gw32:

exercise: 1.9 ± 0.8

control: 1.3 ± 0.6 (n.s.)

gw36:

exercise: 4.8 ± 0.6

control: 4.2 ± 0.6 (p = 0.04)

gw36:

exercise: 4.8 ± 0.6

control: 4.2 ± 0.6 (p = 0.03)

gw36:

exercise: 2.6 ± 0.8

control: 2.0 ± 0.4 (p = 0.01)

gw36:

exercise: 2.3 ± 0.9

control: 1.4 ± 0.7 (p = 0.02)

Satyapriya [36]

Changes in maternal HRV pre and during exercise session and pre and post exercise session (acute effects) at gw20 and gw36 (effects over time)

Important: differences between maternal HRV measurements at gw20 and gw36 (effects over time) were not reported to be tested for significance

 

maternal

pre (gw20) and post (gw36) intervention

maternal

pre (gw20) and post (gw36) intervention

---

gw20:

exercise

pre session: 74.8 ± 5.9

post session: 74.1 ± 6.6 (n.s.)

control

pre session: 73.3 ± 8.0

post session: 70.5 ± 11.6 (n.s.)

gw20:

exercise

pre session: 25.2 ± 5.9

post session: 26.0 ± 6.6 (n.s.)

control

pre session: 26.7 ± 8.0

post session: 29.4 ± 11.6 (n.s.)

gw36:

exercise

pre session: 76.3 ± 4.9

post session: 72.5 ± 6.0 (p = 0.001)

control

pre session: 74.2 ± 9.5

post session: 70.9 ± 7.4 (n.s.)

gw36:

exercise

pre session: 23.2 ± 4.9

post session: 27.5 ± 6.0 (p = 0.001)

control

pre session: 25.0 ± 7.2

post session: 29.1 ± 7.4 (p = 0.006)

  1. (F fetal, gw gestational week, HF high frequency, HRV heart rate variability, IntF intermediate frequency, LF low frequency, LTPA leisure-time physical activity, M maternal, ms millisecond, NW normal weight, n.s not significant, OaO overweight and obese, SE standard error, sig significant, VLF very low frequency)
  2. *p-values were not provided
  3. adata were log transformed to fulfil Gaussian distribution
  4. bkcal · min−1
  5. cminutes during third trimester
  6. dlevel of significance was defined as p ≤ 0.05 for all analyzes performed by Van Leeuwen et al. [41]
  7. emeasurements are only presented for active fetal state. Note that sample size is reduced at all time points (GA weeks 28 (n = 39), 32 (n = 37), 36 (N = 29)); results for quiet fetal state are not presented in this table because sample size is very small in this group