Skip to main content

Table 3 Outcome measurements of each study

From: The influence of physical activity during pregnancy on maternal, fetal or infant heart rate variability: a systematic review

First author, year

Type of analyses

SDNN (ms)

RMSSD (ms)

TP (ms2)

May, [47]

Difference in maternal HRV between exercise and control group at gw28, gw32, and gw36

maternal

gw28:

exercise: 53.9 ± 27.4

control: 38.7 ± 12.9 (p = 0.01)

maternal

gw28:

exercise: 40.2 ± 34.1

control 25.9 ± 13.5 (p = 0.05)d

---

gw32:

exercise: 53.0 ± 19.8

control: 38.1 ± 13.7 (p = 0.002)

gw32:

exercise: 32.7 ± 24.9

control: 22.9 ± 11.7 (n.s.)

gw36:

exercise: 55.8 ± 20.6

control: 44.6 ± 14.0 (p = 0.03)

gw36:

exercise: 32.4 ± 24.9

control: 21.3 ± 11.2 (p = 0.05)d

Van Leeuwen, [41]

Examining the occurrence of fetal-maternal heart rate synchronization in which the mothers were either exercising regularly or were sedentary

maternal

exercise: 57.6 ± 22.2

control: 44.9 ± 12.5 (n.s.)

maternal

exercise: 35.2 ± 26.9

control: 20.8 ± 9.1 (n.s.)

---

fetal

exercise: 29.3 ± 9.6

control: 21.4 ± 6.2 (p = 0.01)

fetal

exercise: 8.6 ± 3.8

control: 6.2 ± 2.1 (p = 0.02)

May, Suminski, [37]

Correlation between continuous and non-continuous maternal LTPA and fetal HRV

fetal

continuous LTPA

R = 0.38 (p < 0.05)

fetal

continuous LTPA

R = 0.31 (n.s.)

---

non-continuous LTPA

R = 0.33 (p < 0.05)

non-continuous LTPA

R = 0.04 (n.s.)

May, Scholtz, [39]

Difference in infant HRV between exercise and control group

infant

exercise: 38.8 ± 10.8

control: 34.8 ± 14.6 (n.s.)

infanta

exercise: 1.03 ± 0.14

control: 0.87 ± 0.21 (p = 0.01)

---

Gustafson, [42]

Difference in fetal HRV between exercise and control group adjusted for fetal breathing

---

fetala

estimate: 0.34; SE: 0.14 (n.s.)

fetala

estimate: 1.06; SE: 0.36 (n.s.)

May, [38]

Correlation between maternal LTPA (intensity, duration) and fetal HRV

Regression to predict fetal heart measures

fetal

intensityb

R = 0.28 (p < 0.05)

fetal

intensityb

R = 0.27 (n.s.)

---

durationc

R = 0.44 (p < 0.005)

durationc

R = 0.39 (p < 0.01)

positively predicted by intensity (p = 0.033)

positively predicted by duration (p = 0.005)

Stutzman [43]

Within and between group changes from pre (gw20) to post (gw36) for each of the four groups; results are only presented for the HRV outcomes measured in supine position

---

---

maternal

exercise – NW:

gw20: 777.1 ± 1072

gw36: 787.8 ± 1042 (n.s.)

exercise – OaO:

gw20: 523.2 ± 621

gw36: 231.9 ± 203.5 (n.s.)

control – NW:

gw20: 746.3 ± 667

gw36: 461.3 ± 583 (n.s.)

control – OaO:

gw20: 652.1 ± 984

gw36: 326.1 ± 506 (sig.)*

May, [40]

Changes in fetal HRV between exercise and control groups depending on fetal state (active vs. passive) at gw28, gw32, and gw36

fetala,e

gw28:

exercise: 3.1 ± 0.3

control 2.9 ± 0.2 (n.s.)

fetala,e

gw28:

exercise: 1.8 ± 0.3

control 1.6 ± 0.3 (n.s.)

---

gw32:

exercise: 3.2 ± 0.3

control: 3.1 ± 0.3 (n.s.)

gw32:

exercise: 1.8 ± 0.3

control: 1.6 ± 0.3 (n.s.)

gw36:

exercise: 3.4 ± 0.3

control: 3.1 ± 0.3 (p = 0.03)

gw36:

exercise: 2.0 ± 0.5

control: 1.7 ± 0.3 (p = 0.03)

Satyapriya [36]

Changes in maternal HRV pre and during exercise session and pre and post exercise session (acute effects) at gw20 and gw36 (effects over time)

Important: differences between maternal HRV measurements at gw20 and gw36 (effects over time) were not reported to be tested for significance

---

---

---

  1. (F fetal, gw gestational week, HRV heart rate variability, LTPA leisure-time physical activity, M maternal, ms millisecond, NW normal weight; n.s not significant, OaO overweight and obese, RMSSD root mean square of successive difference, SE standard error, sig significant, SDNN standard deviation of normal-to-normal intervals, TP total power)
  2. *p-values were not provided
  3. adata were log transformed to fulfill Gaussian distribution
  4. bkcal · min−1
  5. cminutes during third trimester
  6. dlevel of significance was defined as p ≤ 0.05 for all analyzes performed by Van Leeuwen et al. [41]
  7. emeasurements are only presented for active fetal state. Note that sample size is reduced at all time points (GA weeks 28 (n = 39), 32 (n = 37), 36 (N = 29)); results for quiet fetal state are not presented in this table because sample size is very small in this group