Time/Sample | Test | N | Biomarker |
---|---|---|---|
Pregnant women between 24–32 weeks | Blood pressure (automated) | 5000 |  |
OGTT (Fasting plasma glucose, 2 Hour Postprandial plasma glucose) | 5000 | Glucose | |
Haemoglobin | 5000 | Haemoglobin | |
HbA1c (glycosylated haemoglobin, Type A1C) | 500 | Glycosylated haemoglobin | |
One aliquot of fasting sample will be frozen at −80 °C for measurement of serum insulin | 1000 | Insulin resistance and insulin secretion through homeostasis model assessment (HOMA) | |
Blood sample to be preserved at−800 C | 5000 | Micronutrients, DNA and protein markers | |
Repeat OGTT after 32Â weeks (Fasting plasma glucose, 2 Hour Postprandial plasma glucose) | 500 | To explore those who develop gestational diabetes after 32Â weeks | |
Cord blood | C-peptide | 100 | Insulin |
Fathers | Fasting blood glucose in fathers | 500 | Glucose |
Mothers (During follow up visits) | Random blood glucose | 5000 | Glucose |
At the end of the study (IV year) | Fasting blood glucose and insulin levels in mother and child | 5000 | Glucose |