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Table 4 Maternal and fetal Doppler velocimetry, and main obstetric outcomes among controls and subjects with undifferentiated connective tissue disease (UCTD), major rheumatic diseases and no criteria for diagnosis

From: The impact of unrecognized autoimmune rheumatic diseases on the incidence of preeclampsia and fetal growth restriction: a longitudinal cohort study

 

Controls n = 597

UCTD n = 131

Major rheumatic diseases n = 68

No criteria for diagnosis n = 150

p

mean (SD)

mean (SD)

mean (SD)

mean (SD)

 

I st trimester Uterine artery PI

1.16 (0.3)

1.64 (0.3)

1.80 (0.4)

1.37 (0.4)

<.001

II nd trimester Uterine artery PI

0.87 (0.4)

1.29 (0.2)

1.33 (0.3)

1.00 (0.3)

<.001

III rd trimester Umbilical Artery PI

0.89 (0.1)

0.95 (0.2)

1.03 (0.3)

0.95 (0.20)

<.001

 

N (%)

N (%)

N (%)

N (%)

 

Uterine artery bilateral notch

 Ist trimester

23 (3.8)

33 (25.2)

30 (44.1)

14 (9.3)

<.001

 IInd trimester

14 (2.3)

15 (11.5)

18 (26.5)

9 (6)

<.001

Umbilical artery PI >95° percentile

25 (4.2)

21 (16)

18 (26.5)

24 (16)

<.001

Miscarriage

2 (0.3)

  

1 (0.6)

0.6

Stillbirth

1 (0.2)

 

1 (1.5)

 

0.3

Gestational diabetes

13 (2.2)

4 (3.1)

4 (5.8)

6 (4.0)

0.35

Small for gestational age

46 (7.7)

23 (17.5)

18 (26.5)

17 (11.3)

<.001

Fetal growth restriction (FGR)

25 (4.2)

21 (16)

18 (26.5)

20 (13.3)

<.001

Preeclampsia

19 (3.2)

18 (13.7)

15 (22.1)

9 (6)

<.001

Preclampsia or FGR

36 (6)

30 (22.9)

20 (29.4)

22 (14.6)

<.001

Delivery less than 34 weeks

17 (2.8)

6 (4.6)

5 (7.4)

4 (2.6)

0.2

Cesarean section

183 (30.6)

58 (44.3)

34 (50)

46 (30.6)

0.001

  1. SD standard deviation, PI pulsatility index
  2. p values obtained by one-way anova or chi-square test