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Table 7 Biological markers of nutritional status in individual studies compared to reference values

From: Nutrient intakes and nutritional biomarkers in pregnant adolescents: a systematic review of studies in developed countries

 

Study ID

First Trimester

Second Trimester

Third Trimester

Delivery

  

N=

Mean

Confidence Interval

N=

Mean

Confidence Interval

N=

Mean

Confidence Interval

N=

Mean

Confidence Interval

Haemoglobin (g/L) a

Baker (2009)

404

↑122

121, 123

   

362

↓108

107, 109

   

Chang (2003)

445

↑121

121, 122

319

↑112

112, 114

836

↓107

107, 109

   

Dawson (2000) a

   

21

↑124

123, 125

21

↑115

114, 116

20

↑114

111, 112

Dawson (2000) b

   

20

↑125

124, 126

20

↑119

118, 120

21

↑116

112, 114

Dawson (2000) a

      

21

↑114

113, 115

   

Dawson (2000) b

      

20

↑120

119, 121

   

Gadowsky (1995)

      

50

↑119

115, 123

   

Iannotti (2005)

   

35

↔111

107, 115

70

↔107

104, 110

   

McGuire Davies (2010)

   

78

↑118

118, 118

76

↓107

107, 108

   

Meier (2002) a

   

20

↑125

122, 129

15

↑123

119, 128

   

Meier (2002) b

   

17

↑128

124, 132

16

↑117

112, 123

   

Meier (2002) a

   

19

↑116

112, 120

      

Meier (2002) b

   

16

↑113

110, 116

      

Rycel (2009)

         

102

↑120

120, 229

Rycel (2009)

         

102

↓103

103, 103

Young (2010)

   

48

↑113

    

62

↑117

113, 121

Ferritin (μg/L or ng/ml) b

Gadowsky (1995)

   

50

↓7.4

5.7, 9.1

      

Iannotti (2005)

   

44

↑33

26.8, 40.6

59

↔15

12.6, 17.8

   

Meier (2002) a

   

19

↑42

31.3, 52.8

15

↔25

14.6, 35.4

   

Meier (2002) b

   

17

↑57

36.5, 77.5

15

↓6.8

5.2, 8.5

   

Meier (2002) a

   

19

↑46

24, 68.8

      

Meier (2002) b

   

16

↓10

7.9, 13

      

Young (2010)

   

81

↔16

12.9, 20.1

   

88

↔17

14.9, 20.3

Haematocrit (g/L) c

Chang (2003)

445

↑36

35.7, 36.3

319

↔33

32.7, 33.3

836

↓32

31.8, 32.2

   

Gadowsky (1995)

      

50

↑36

34.8, 37.2

   

Iannotti (2005)

   

35

↔33

32, 34

70

↓32

31.3, 32.7

   

Rycel (2009)

         

102

34

34.6, 34.8

Rycel (2009)

         

102

↓31

31.4, 31.6

Zinc μmol/L-1 d

Castillo-Duran (2001) a

249

↑11.9

11.7, 12.1

   

249

↑10.9

10.7, 11.1

   

Castillo-Duran (2001) b

258

↑11.7

11.5, 11.9

   

258

↑10.9

10.7, 11.1

   

Castillo-Duran (2001) a

      

249

↑10.5

10.3, 10.7

   

Castillo-Duran (2001) b

      

258

↑10.2

10, 10.4

   

Chan (2006)

         

23

↑26.3

23.2, 29.4

Mistry (2014) a

      

107

↑9.71

8.8, 10.5

   

Mistry (2014) b

      

19

↑10.8

7.8, 13.9

   

Magnesium mmol/l e

Chan (2006)

         

23

↑0.99

0.9, 1.1

Phosphorous mg/dl f

Chan (2006)

         

23

↑5

4, 6

Copper μg/dl g

Mistry (2014) a

      

107

↑206

1991, 2128

   

Mistry (2014) b

      

19

↑196

1712, 2207

   

Selenium μg/L h

Dawson (2000) a

   

21

↓49

46, 52

21

↓55

52.9, 57.1

21

↑114

108.9, 119.1

Dawson (2000) b

   

20

↓44

39.6, 48.4

20

↓53

50.8, 55.2

20

↓55

50.2, 59.8

Dawson (2000) a

   

21

↓50

46.2, 53.8

21

↔85

76.9, 93.1

   

Dawson (2000) b

   

20

↓44

39.6, 48.4

20

↓62

57.2, 66.8

   

Mistry (2014) a

      

107

↓65

62.7, 67.5

   

Mistry (2014) b

      

19

↓49

45.9, 52.9

   

Red blood cell folate (nmol/l) i

Baker (2009)

      

266

↑647

616, 680

   

Serum folate (nmol/l) j

Baker (2009)

      

291

↑12

12, 14

   

Chan (2006)

         

23

↔13

10, 17

Vitamin A (μg/dL)

Chan (2006)

         

23

↑38

31, 45

B12 (pmol/l) k

Baker (2009)

      

293

↑177

169, 185

   

Chan (2006)

         

23

↑265

216, 315

Gadowsky (1995)

      

50

↑170

146, 194

   

Homocysteine (μmol/L) l

Baker (2009)

      

293

7.9

7.6, 8.2

   

Gadowsky (1995)

      

50

6.1

3, 9

   

25OHD (nmol/L) m

Baker (2009)

      

263

↑33

30.4, 35.8

   

Chan (2006)

         

23

↑57

48, 67

Ginde (2010)

            

McGuire Davies (2010)

   

44

↑52

46, 58

36

↑56

50, 63

   

O’Brien (2003)

      

23

↑50

41, 60

   

Young (2012)

         

171

↑54

51, 59

  1. a Target value 110 g/L, b Target value 15 μg/L, c Target value33 g/L, d Target value 6.12 μmol/L-1, e Target value 0.9 mmol/L, f Target value 2.5 mg/dl, g Target value 63.7 μg/dl, h Target value 90 μg/L, i Target value 340 nmol/L, j Target value 20 μg/dl, k Target value 150pmol/L, l Target value less than 13 μmol/L, m Target value 25 nmol/L, ↑ Study mean higher than reference value (p < 0.05), ↔ Study mean not different to reference value (p < 0.05), ↓ Study mean lower than reference value (p < 0.05)