|
Mean ± SD
|
---|
Pooled MTDa
n = 26
|
Pooled Placeboa
n = 23
|
---|
Cervical Dilatation (cm)
|
0.63 ± 0.81
|
1.35 ± 1.21
|
Effacement (%)
|
0.43 ± 0.59
|
0.65 ± 0.75
|
Station
|
0.50 ± 1.45
|
0.44 ± 0.71
|
Consistency
|
0.83 ± 0.78
|
0.92 ± 0.63
|
Position of Cervix
|
0.83 ± 0.83
|
1.19 ± 0.69
|
- Mean changes from baseline in the individual components of the Bishop score at 24 h were calculated post-hoc in all patients receiving 24 h of study drug with Bishop scores available at baseline and 24 h
-
aPooled Maximum Tolerated Dose (MTD) group includes subjects who were administered the 75 μg/kg/day dose in Parts A and B of the study. Pooled placebo group includes subjects who received placebo in Parts A and B