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Table 3 Mortality among registry births ≥1500 g pre-post HBB intervention stratified by birth weight

From: A pre-post study of a multi-country scale up of resuscitation training of facility birth attendants: does Helping Babies Breathe training save lives?

  Birth weight 1500–2499 g  ≥ 2500 g
Estimatesa of Mortality Rates (95 % CI) P-value Estimatesa of Mortality Rates (95 % CI) P-value
Pre Post Difference Pre Post Difference
All registry births 3853 5000    31,405 29,922   
 Perinatal deaths 139.4 (112.9, 166.0) 122.7 (96.1, 149.2) 16.7 (−12.1, 45.5) 0.25 14.6 (12.2, 17.0) 14.3 (11.9, 16.7) 0.3 (−2.1, 2.7) 0.82
 Fresh stillbirths 72.1 (51.4, 92.8) 55.0 (34.3, 75.7) 17.1 (−6.8, 41.0) 0.16 7.1 (5.4, 8.9) 6.1 (4.4, 7.9) 1.0 (−0.9, 2.9) 0.28
 ENDb by day 7 73.1 (55.4, 90.8) 71.8 (54.1, 89.5) 1.3 (−20.9, 23.5) 0.91 7.5 (6.0, 9.0) 8.2 (6.7, 9.7) −0.7 (−2.4, 0.9) 0.38
Kenya 256 267    8429 8145   
 Perinatal deaths 234.3 (174.0, 294.6) 212.5 (152.2, 272.8) 21.8 (−63.5, 107.1) 0.59 20.3 (15.0, 25.7) 18.2 (12.9, 23.6) 2.1 (−3.4, 7.6) 0.43
 Fresh stillbirths 143.4 (87.4, 199.3) 107.0 (51.1, 162.9) 36.4 (−42.2, 114.9) 0.34 13.9 (9.9, 18.0) 10.6 (6.6, 14.7) 3.3 (−1.9, 8.5) 0.19
 ENDb by day 7 105.1 (58.6, 151.7) 115.3 (68.8, 161.9) −10.2 (−76.0, 55.6) 0.75 6.5 (3.6, 9.3) 7.7 (4.8, 10.5) −1.2 (−4.2, 1.7) 0.39
Nagpur, India 1336 1441    8152 8336   
 Perinatal deaths 103.6 (78.9, 128.3) 104.6 (79.9, 129.3) −1.0 (−24.3, 22.4) 0.93 10.5 (6.8, 14.1) 11.6 (8.0, 15.2) −1.2 (−5.3, 3.0) 0.57
 Fresh stillbirths 41.5 (25.6, 57.3) 40.6 (24.8, 56.4) 0.9 (−17.4, 19.1) 0.92 3.9 (2.2, 5.7) 4.1 (2.4, 5.9) −0.2 (−2.7, 2.3) 0.87
 ENDb by day 7 64.2 (40.8, 87.6) 66.4 (43.1, 89.8) −2.2 (−25.7, 21.3) 0.85 6.6 (3.8, 9.3) 7.5 (4.8, 10.3) −1.0 (−3.6, 1.7) 0.46
Belgaum, India 2261 3292    14,824 13,441   
 Perinatal deaths 89.2 (75.8, 102.6) 55.4 (42.0, 68.9) 33.8 (16.4, 51.2) < 0.001 14.0 (11.1, 16.9) 13.8 (10.8, 16.7) 0.2 (−3.1, 3.5) 0.89
 Fresh stillbirths 39.2 (30.2, 48.1) 21.1 (12.1, 30.0) 18.1 (5.5, 30.7) <.01 4.4 (2.8, 6.0) 4.1 (2.5, 5.7) 0.2 (−1.5, 1.9) 0.78
 ENDb by day 7 52.2 (41.8, 62.7) 35.0 (24.6, 45.5) 17.2 (3.3, 31.1) 0.02 9.7 (7.1, 12.3) 9.7 (7.1, 12.3) −0.0 (−3.6, 3.6) 1.00
HBB Facility Births 1988 2550    13,205 13,393   
 Perinatal deaths 140.1 (102.9, 177.4) 102.8 (65.5, 140.0) 37.4 (−15.3, 90.1) 0.16 18.8 (14.4, 23.2) 15.9 (11.5, 20.4) 2.9 (−1.9, 7.7) 0.23
 Fresh stillbirths 71.4 (40.8, 102.0) 38.1 (7.5, 68.7) 33.3 (−10.0, 76.6) 0.13 10.4 (7.0, 13.8) 7.2 (3.8, 10.7) 3.2 (−0.8, 7.2) 0.12
 ENDb by day 7 76.5 (52.2, 100.8) 66.4 (42.3, 90.4) 10.2 (−23.7, 44.0) 0.55 8.4 (5.8, 11.1) 8.8 (6.1, 11.4) −0.3 (−3.6, 2.9) 0.84
Kenya 146 152    3073 3319   
 Perinatal deaths 266.6 (160.4, 372.8) 149.2 (43.0, 255.4) 117.4 (−32.7, 267.6) 0.12 32.9 (22.4, 43.5) 22.0 (11.5, 32.6) 10.9 (−0.6, 22.4) 0.06
 Fresh stillbirths 148.5 (50.1, 246.8) 48.7 (−49.7, 147.0) 99.8 (−39.2, 238.9) 0.15 24.5 (16.2, 32.8) 14.3 (6.0, 22.6) 10.2 (−1.3, 21.8) 0.08
 ENDb by day 7 143.6 (71.5, 215.8) 101.9 (32.0, 171.8) 41.7 (−58.7, 142.2) 0.39 8.6 (4.3, 12.8) 7.9 (3.6, 12.1) 0.7 (−3.0, 4.4) 0.69
Nagpur, India 628 695    3411 3676   
 Perinatal deaths 100.7 (72.8, 128.6) 114.4 (86.5, 142.3) −13.7 (−53.2, 25.8) 0.48 13.5 (7.0, 20.0) 14.2 (7.8, 20.7) −0.7 (−8.8, 7.3) 0.85
 Fresh stillbirths 44.1 (27.6, 60.7) 49.7 (33.1, 66.2) −5.5 (−28.6, 17.5) 0.62 5.1 (1.7, 8.5) 5.6 (2.2, 8.9) −0.5 (−5.3, 4.3) 0.83
 ENDb by day 7 59.0 (34.0, 83.9) 67.9 (42.9, 92.8) −8.9 (−43.5, 25.7) 0.60 8.4 (2.3, 14.5) 8.7 (2.6, 14.8) −0.3 (−8.0, 7.4) 0.94
Belgaum, India 1214 1703    6721 6398   
 Perinatal deaths 62.9 (48.8, 77.1) 41.7 (27.6, 55.9) 21.2 (3.9, 38.5) 0.02 11.3 (8.0, 14.7) 12.0 (8.6, 15.3) −0.7 (−5.0, 3.7) 0.75
 Fresh stillbirths 28.5 (18.9, 38.1) 13.2 (3.6, 22.8) 15.3 (1.7, 28.9) 0.03 3.0 (1.5, 4.5) 2.3 (0.7, 3.8) 0.8 (−0.9, 2.4) 0.34
 ENDb by day 7 35.6 (26.8, 44.3) 28.9 (20.2, 37.6) 6.7 (−4.7, 18.0) 0.23 8.3 (5.5, 11.2) 9.7 (6.8, 12.6) −1.4 (−5.5, 2.7) 0.48
  1. a Estimated means obtained from a mixed model with cluster as a random factor and time period as a fixed factor
  2. b END early neonatal death