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Table 3 Mortality among registry births ≥1500 g pre-post HBB intervention stratified by birth weight

From: A pre-post study of a multi-country scale up of resuscitation training of facility birth attendants: does Helping Babies Breathe training save lives?

 

Birth weight 1500–2499 g

 ≥ 2500 g

Estimatesa of Mortality Rates (95 % CI)

P-value

Estimatesa of Mortality Rates (95 % CI)

P-value

Pre

Post

Difference

Pre

Post

Difference

All registry births

3853

5000

  

31,405

29,922

  

 Perinatal deaths

139.4 (112.9, 166.0)

122.7 (96.1, 149.2)

16.7 (−12.1, 45.5)

0.25

14.6 (12.2, 17.0)

14.3 (11.9, 16.7)

0.3 (−2.1, 2.7)

0.82

 Fresh stillbirths

72.1 (51.4, 92.8)

55.0 (34.3, 75.7)

17.1 (−6.8, 41.0)

0.16

7.1 (5.4, 8.9)

6.1 (4.4, 7.9)

1.0 (−0.9, 2.9)

0.28

 ENDb by day 7

73.1 (55.4, 90.8)

71.8 (54.1, 89.5)

1.3 (−20.9, 23.5)

0.91

7.5 (6.0, 9.0)

8.2 (6.7, 9.7)

−0.7 (−2.4, 0.9)

0.38

Kenya

256

267

  

8429

8145

  

 Perinatal deaths

234.3 (174.0, 294.6)

212.5 (152.2, 272.8)

21.8 (−63.5, 107.1)

0.59

20.3 (15.0, 25.7)

18.2 (12.9, 23.6)

2.1 (−3.4, 7.6)

0.43

 Fresh stillbirths

143.4 (87.4, 199.3)

107.0 (51.1, 162.9)

36.4 (−42.2, 114.9)

0.34

13.9 (9.9, 18.0)

10.6 (6.6, 14.7)

3.3 (−1.9, 8.5)

0.19

 ENDb by day 7

105.1 (58.6, 151.7)

115.3 (68.8, 161.9)

−10.2 (−76.0, 55.6)

0.75

6.5 (3.6, 9.3)

7.7 (4.8, 10.5)

−1.2 (−4.2, 1.7)

0.39

Nagpur, India

1336

1441

  

8152

8336

  

 Perinatal deaths

103.6 (78.9, 128.3)

104.6 (79.9, 129.3)

−1.0 (−24.3, 22.4)

0.93

10.5 (6.8, 14.1)

11.6 (8.0, 15.2)

−1.2 (−5.3, 3.0)

0.57

 Fresh stillbirths

41.5 (25.6, 57.3)

40.6 (24.8, 56.4)

0.9 (−17.4, 19.1)

0.92

3.9 (2.2, 5.7)

4.1 (2.4, 5.9)

−0.2 (−2.7, 2.3)

0.87

 ENDb by day 7

64.2 (40.8, 87.6)

66.4 (43.1, 89.8)

−2.2 (−25.7, 21.3)

0.85

6.6 (3.8, 9.3)

7.5 (4.8, 10.3)

−1.0 (−3.6, 1.7)

0.46

Belgaum, India

2261

3292

  

14,824

13,441

  

 Perinatal deaths

89.2 (75.8, 102.6)

55.4 (42.0, 68.9)

33.8 (16.4, 51.2)

< 0.001

14.0 (11.1, 16.9)

13.8 (10.8, 16.7)

0.2 (−3.1, 3.5)

0.89

 Fresh stillbirths

39.2 (30.2, 48.1)

21.1 (12.1, 30.0)

18.1 (5.5, 30.7)

<.01

4.4 (2.8, 6.0)

4.1 (2.5, 5.7)

0.2 (−1.5, 1.9)

0.78

 ENDb by day 7

52.2 (41.8, 62.7)

35.0 (24.6, 45.5)

17.2 (3.3, 31.1)

0.02

9.7 (7.1, 12.3)

9.7 (7.1, 12.3)

−0.0 (−3.6, 3.6)

1.00

HBB Facility Births

1988

2550

  

13,205

13,393

  

 Perinatal deaths

140.1 (102.9, 177.4)

102.8 (65.5, 140.0)

37.4 (−15.3, 90.1)

0.16

18.8 (14.4, 23.2)

15.9 (11.5, 20.4)

2.9 (−1.9, 7.7)

0.23

 Fresh stillbirths

71.4 (40.8, 102.0)

38.1 (7.5, 68.7)

33.3 (−10.0, 76.6)

0.13

10.4 (7.0, 13.8)

7.2 (3.8, 10.7)

3.2 (−0.8, 7.2)

0.12

 ENDb by day 7

76.5 (52.2, 100.8)

66.4 (42.3, 90.4)

10.2 (−23.7, 44.0)

0.55

8.4 (5.8, 11.1)

8.8 (6.1, 11.4)

−0.3 (−3.6, 2.9)

0.84

Kenya

146

152

  

3073

3319

  

 Perinatal deaths

266.6 (160.4, 372.8)

149.2 (43.0, 255.4)

117.4 (−32.7, 267.6)

0.12

32.9 (22.4, 43.5)

22.0 (11.5, 32.6)

10.9 (−0.6, 22.4)

0.06

 Fresh stillbirths

148.5 (50.1, 246.8)

48.7 (−49.7, 147.0)

99.8 (−39.2, 238.9)

0.15

24.5 (16.2, 32.8)

14.3 (6.0, 22.6)

10.2 (−1.3, 21.8)

0.08

 ENDb by day 7

143.6 (71.5, 215.8)

101.9 (32.0, 171.8)

41.7 (−58.7, 142.2)

0.39

8.6 (4.3, 12.8)

7.9 (3.6, 12.1)

0.7 (−3.0, 4.4)

0.69

Nagpur, India

628

695

  

3411

3676

  

 Perinatal deaths

100.7 (72.8, 128.6)

114.4 (86.5, 142.3)

−13.7 (−53.2, 25.8)

0.48

13.5 (7.0, 20.0)

14.2 (7.8, 20.7)

−0.7 (−8.8, 7.3)

0.85

 Fresh stillbirths

44.1 (27.6, 60.7)

49.7 (33.1, 66.2)

−5.5 (−28.6, 17.5)

0.62

5.1 (1.7, 8.5)

5.6 (2.2, 8.9)

−0.5 (−5.3, 4.3)

0.83

 ENDb by day 7

59.0 (34.0, 83.9)

67.9 (42.9, 92.8)

−8.9 (−43.5, 25.7)

0.60

8.4 (2.3, 14.5)

8.7 (2.6, 14.8)

−0.3 (−8.0, 7.4)

0.94

Belgaum, India

1214

1703

  

6721

6398

  

 Perinatal deaths

62.9 (48.8, 77.1)

41.7 (27.6, 55.9)

21.2 (3.9, 38.5)

0.02

11.3 (8.0, 14.7)

12.0 (8.6, 15.3)

−0.7 (−5.0, 3.7)

0.75

 Fresh stillbirths

28.5 (18.9, 38.1)

13.2 (3.6, 22.8)

15.3 (1.7, 28.9)

0.03

3.0 (1.5, 4.5)

2.3 (0.7, 3.8)

0.8 (−0.9, 2.4)

0.34

 ENDb by day 7

35.6 (26.8, 44.3)

28.9 (20.2, 37.6)

6.7 (−4.7, 18.0)

0.23

8.3 (5.5, 11.2)

9.7 (6.8, 12.6)

−1.4 (−5.5, 2.7)

0.48

  1. a Estimated means obtained from a mixed model with cluster as a random factor and time period as a fixed factor
  2. b END early neonatal death