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Table 2 Haemoglobin concentration and the risk of stillbirth

From: Maternal haemoglobin concentrations before and during pregnancy and stillbirth risk: a population-based case-control study

 

Cases

Controls

Odds Ratio (95 % Confidence Interval)

n (%)

n (%)

Crude

Adjusteda

Haemoglobin concentration before pregnancy (g/l)

  < 110

4 (2.5)

31 (2.5)

1.04 (0.36–3.04)

1.23 (0.39–3.84)

 110–120

72 (45.6)

582 (47.5)

Reference

Reference

 121–139

49 (31.0)

360 (29.4)

1.10 (0.75–1.61)

0.97 (0.64–1.47)

  ≥ 140

33 (20.9)

252 (21.0)

1.06 (0.68–1.64)

0.83 (0.52–1.34)

 Continuous

158 (100)

1,225 (100)

1.00 (0.99–1.02)

1.00 (0.98–1.01)

Haemoglobin concentration at first trimester (g/l) (gestational age weeks between 6 to 10)

  < 110

26 (5.3)

181 (6.5)

0.91 (0.59–1.40)

0.87 (0.55–1.37)

 110–120

223 (46.1)

1,411 (50.5)

Reference

Reference

 121–139

152 (31.4)

834 (30.0)

1.45 (0.92–1.44)

1.18 (0.94–1.49)

  ≥ 140

83 (17.1)

366 (13.1)

1.43 (1.09–1.89)

1.36 (1.01–1.81)

 Continuous

484 (100)

2,792 (100)

1.01 (1.00–1.02)

1.01 (1.00–1.02)

Haemoglobin concentration at end of second trimester(g/l) (gestational age weeks between 26 to 30)

  < 110

37 (14.0)

523 (21.2)

0.64 (0.44–0.92)

0.63 (0.43–0.92)

 110–120

180 (65.2)

1,618 (65.6)

Reference

Reference

 121–139

40 (14.4)

268 (10.9)

1.34 (0.93–1.93)

1.19 (0.81–1.74)

  ≥ 140

18 (6.4)

59 (2.4)

2.74 (1.58–4.75)

2.31 (1.30–4.10)

 Continuous

275 (100)

2,468 (100)

1.03 (1.02–1.04)

1.03 (1.01–1.04)

  1. aAdjusted for maternal age, maternal height, maternal BMI, parity, smoking status, husband’s profession, region and gestational age at haemoglobin measurement