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Table 2 Factors associated with a maternal positive HSV-2 serostatus

From: High prevalence of herpes simplex virus (HSV)- type 2 co-infection among HIV-positive women in Ukraine, but no increased HIV mother-to-child transmission risk

 

Proportion of women with HSV-2 antibodies

PR (95 % CI)

p value

Adjusted PR (95 % CI) n = 1095

p value

Maternal age

 16–23 years

57 % (155/271)

1.00

 

1.00

 

 24–26 years

67 % (302/450)

1.19 (1.04–1.37)

0.014

1.11 (0.97–1.28)

0.137

 27–30 years

73 % (319/438)

1.25 (1.09–1.44)

0.002

1.09 (0.95–1.26)

0.218

 ≥31 years

71 % (249/353)

1.23 (1.07–1.43)

0.004

1.03 (0.88–1.21)

0.676

Parity

 0

62 % (402/647)

1.00

 

1.00

 

 1

70 % (392/557)

1.13 (1.03–1.23)

0.009

1.01 (0.91–1.10)

0.913

 ≥2

75 % (165/219)

1.14 (1.01–1.28)

0.027

0.99 (0.87–1.12)

0.857

History of pregnancy termination

 0

57 % (373/653)

1.00

 

1.00

 

 1

73 % (214/293)

1.24 (1.11–1.38)

<0.001

1.22 (1.10–1.36)

<0.001

 ≥2

79 % (357/452)

1.36 (1.25–1.49)

<0.001

1.30 (1.18–1.43)

<0.001

Pregnancy planned

 No

71 % (320/450)

1.00

 

1.00

 

 Yes

66 % (696/1051)

0.96 (0.88–1.05)

0.343

1.03 (0.94–1.13)

 

History of IDU

 No

66 % (800/1209)

1.00

 

1.00

 

 Yes

74 % (218/295)

1.05 (0.96–1.16)

0.299

0.93 (0.83–1.03)

0.174

Partner’s HIV statusa

 Unknown

63 % (238/375)

1.00

 

1.00

 

 Negative

59 % (210/354)

0.90 (0.79–1.04)

0.147

0.91 (0.79–1.05)

0.184

 Positive

77 % (477/623)

1.21 (1.10–1.33)

<0.001

1.15 (1.05–1.26)

0.003

HCV serostatus

 Negative

63 % (589/933)

1.00

 

1.00

 

 Positive

81 % (380/469)

1.25 (1.16–1.35)

<0.001

1.23 (1.13–1.35)

<0.001

Hepatitis B surface antigen

 Negative

65 % (756/1165)

1.00

 

1.00

 

 Positive

78 % (224/286)

1.20 (1.11–1.31)

<0.001

1.06 (0.97–1.16)

0.179

  1. a As reported by the woman