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Table 2 Comparison of the pregnancy outcomes between asymptomatic HBV carriers and non-HBV controlsa

From: Maternal hepatitis B virus carrier status and pregnancy outcomes: a prospective cohort study

Outcome HBV carriers (n = 513) Controls (n = 20,491) P
Completed weeks’ gestation 35.79 ± 8.29 36.95 ± 6.76 <0.001
 ≤12 wks 36 822 0.002
 12 1/7 to 28 wks 13 390  
 28 1/7 to 40 wks 369 14,755  
 >40 wks 95 4,524  
Preterm birth 49 (9.55 %) 1,718 (8.38 %) 0.347
Stillbirth 0 18 (0.09 %) 0.502
Miscarriage 48 (9.36 %) 1,167 (5.70 %) <0.001
Preeclampsia 4 (0.78 %) 216 (1.05 %) 0.600
GDM 6 (1.17 %) 232 (1.13 %) 0.937
ICP 12 (2.34 %) 331 (1.62 %) 0.201
Placenta previa 4 (0.78 %) 216 (1.05 %) 0.547
PPROM 23 (4.48 %) 845 (4.12 %) 0.686
  1. Abbreviations: GDM Gestational diabetes, ICP intrahepatic cholestasis of pregnancy, PPROM preterm premature rupture of the membrane
  2. aValues are reported as mean ± SD, compared with t test, or number (percentage), compared with χ 2 test, unless otherwise indicated