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Table 3 Summary of different comparative results of serum RBP4 level with GDM risk

From: Serum level and polymorphisms of retinol-binding protein-4 and risk for gestational diabetes mellitus: a meta-analysis

Category

 

No of study

No of case

No of control

SMD (95 % CI)

Z

p value

I2%

P het

overall

 

17

647

620

0.816 [0.411–1.122]

3.94

0.000

91.0

0.000

Gestational age at blood sampling

Before 24 weeks

1

32

44

-0.426 [-0.886–0.035]

1.81

0.070

-

-

 

24-28 weeks

10

390

386

0.561 [0.252–0.870]

3.56

0.000

74.8

0.000

 

After 28 weeks

5

205

170

1.830 [0.580– 3.080]

2.87

0.004

96.0

0.000

 

Postpartum

1

20

20

-0.076 [-0.696–0.544]

0.24

0.810

-

-

Diagnostic criteria

ADA criteria

8

347

310

0.205 [-0.063–0.472]

1.50

0.134

61.7

0.011

 

Rigorous criteria

9

300

310

1.388 [0.665–2.110]

3.77

0.000

91.0

0.000

  1. P het = p value for heterogeneity, OR = adds ratio, CI = confidence interval, ADA = American Diabetes Association criteria, More rigorous criteria contained National Diabetes Data Group criteria, World Health Organization criteria and the criteria of Sun et al