Table 2 Pre-term outcome overall and for HIV + ve only
From: Improved pregnancy outcomes with increasing antiretroviral coverage in South Africa
All women | Bivariate | Multivariable iv | ||||
|---|---|---|---|---|---|---|
Variable | Term n (% i) | Pre-term <37w) n (%) | p-value ii | 0R iii (95 % CI) | 0R (95 % CI) | adj p-value |
Year | ||||||
2011 | 3409 (78.03) | 960 (21.97) | 0.002 | 1 (ref) | 1 (ref) | |
2014 | 4412 (80.54) | 1066 (19.46) | 0.86 (0.78–0.95) | 0.94 (0.83–1.06) | 0.291 | |
Age Category | ||||||
< 18 | 643 (77.75) | 184 (22.25) | 0.053 | 1 (ref) | 1 (ref) | |
18–24 | 3421 (78.54) | 935 (21.46) | 0.96 (0.8–1.14) | 0.92 (0.77–1.1) | 0.362 | |
25–34 | 2945 (80.42) | 717 (19.58) | 0.85 (0.71–1.02) | 0.78 (0.64–0.94) | 0.01 | |
> 34 | 726 (81.3) | 167 (18.7) | 0.8 (0.64–1.02) | 0.73 (0.57–0.93) | 0.012 | |
Mode of Delivery | ||||||
Vaginal | 5365 (80.27) | 1319 (19.73) | <0.001 | 1 (ref) | 1 (ref) | |
Emergency Caesarean | 1100 (75.5) | 357 (24.5) | 1.32 (1.15–1.51) | 1.3 (1.12–1.51) | 0.001 | |
Planned Caesarean | 1346 (79.69) | 343 (20.31) | 1.04 (0.91–1.18) | 1.07 (0.93–1.24) | 0.319 | |
HIV | ||||||
Negative | 4820 (81.47) | 1096 (18.53) | <0.001 | 1 (ref) | 1 (ref) | |
Positive | 2893 (77.71) | 830 (22.29) | 1.26 (1.14–1.4) | 1.33 (1.19–1.48) | <0.001 | |
Unregistered Antenatal | 102 (51) | 98 (49) | 4.23 (3.18–5.62) | 4.24 (3.18–5.64) | <0.001 | |
HIV + ve women only | Bivariate | Multivariable v | ||||
Variable | Term n (% i) | Pre-term (<37w) n (%) | p-value ii | 0R (95 % CI) | 0R (95 % CI) | adj p-value |
Year | ||||||
2011 | 1249 (77.19) | 369 (22.81) | 0.51 | 1 (ref) | 1 (ref) | |
2014 | 1644 (78.1) | 461 (21.9) | 0.95 (0.81–1.11) | 0.63 (0.27–1.44) | 0.269 | |
Age Category | ||||||
< 18 | 69 (74.19) | 24 (25.81) | 0.849 | 1 (ref) | 1 (ref) | |
18–24 | 925 (77.8) | 264 (22.2) | 0.82 (0.51–1.33) | 1.14 (0.32–4.01) | 0.84 | |
25–34 | 1482 (77.88) | 421 (22.12) | 0.82 (0.51–1.32) | 1.26 (0.36–4.4) | 0.717 | |
> 34 | 395 (78.37) | 109 (21.63) | 0.79 (0.48–1.32) | 1.35 (0.36–5) | 0.655 | |
Mode of Delivery | ||||||
Vaginal | 1940 (78.51) | 531 (21.49) | 0.13 | 1 (ref) | 1 (ref) | |
Emergency Caesarean | 420 (74.6) | 143 (25.4) | 1.24 (1.01–1.54) | 1.43 (1–2.06) | 0.05 | |
Planned Caesarean | 526 (77.47) | 153 (22.53) | 1.06 (0.87–1.3) | 0.82 (0.49–1.37) | 0.456 | |
CD4 category | ||||||
< 200 | 274 (80.35) | 67 (19.65) | 0.582 | 1 (ref) | 1 (ref) | |
201–350 | 282 (82.22) | 61 (17.78) | 0.88 (0.6–1.3) | 0.87 (0.58–1.29) | 0.478 | |
351–500 | 275 (81.36) | 63 (18.64) | 0.94 (0.64–1.37) | 0.92 (0.6–1.39) | 0.686 | |
> 500 | 136 (77.27) | 40 (22.73) | 1.2 (0.77–1.87) | 1.16 (0.72–1.88) | 0.545 | |
ART regimen | ||||||
Nil ARVs | 100 (67.57) | 48 (32.43) | 0.002 | 1 (ref) | 1 (ref) | |
AZT/NVP | 778 (79.88) | 196 (20.12) | 0.52 (0.36–0.77) | 0.2 (0.08–0.51) | 0.001 | |
D4T/3TC/NVP | 685 (75.52) | 222 (24.48) | 0.68 (0.46–0.98) | 0.21 (0.08–0.55) | 0.001 | |
EFV/TDF/FTC | 1315 (78.93) | 351 (21.07) | 0.56 (0.39–0.8) | 0.31 (0.11–0.9) | 0.031 |