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Table 1 DNA Methylation and immune function

From: Childbirth and consequent atopic disease: emerging evidence on epigenetic effects based on the hygiene and EPIIC hypotheses

Immune function or Alteration

Reference

Bacterial infection induces hypermethylation

[37]

Discriminates between regulatory and conventional T cells

[75]

Downregulation of IFN-γ in fetus, helps prevent fetal loss

[76]

Early-life stress alters T-cell methylation

[69]

IgE production

[77]

Immune cell signaling and communication pathways

[34]

Maintenance of T cell memory and cytokine expression pattern

[35]

Maternal bacterial infection promotes fetal hypermethylation

[78]

Number and function of regulatory T cells

[79]

Viral infection increases DNA methylation

[36]