Folic acid supplementation, preconception body mass index, and preterm delivery: findings from the preconception cohort data in a Chinese rural population

Wang, Yuanyuan; Cao, Zongfu; Peng, Zuoqi; Xin, Xiaona; Zhang, Ya; Yang, Ying; He, Yuan; Xu, Jihong; Ma, Xu

doi:10.1186/s12884-015-0766-y

Table 1 Maternal characteristics in study population grouped by preconception body mass index and folic acid supplement

From: Folic acid supplementation, preconception body mass index, and preterm delivery: findings from the preconception cohort data in a Chinese rural population

	Preconception body mass index(kg²)				P	Folic acid supplement			P
	<18.5	18.5-23.9	24-27.9	≥28	P	Never	1st trimester	Preconception	P
Maternal characteristics
No of subject	23429	129982	15880	2915		39871	41457	90878
Demographic information (%)
Maternal age (yr)	24.96(3.19)	24.18(3.82)	26.01(4.54)	26.60(4.70)	<0.001	24.85(3.94)	24.77(3.69)	25.13(3.90)	<0.001
Maternal education level
Primary school	4.72	4.96	6.78	8.03	<0.001	5.01	4.51	5.50	<0.001
Junior school	60.56	67.38	71.79	72.42		73.50	63.63	65.57
High school	21.82	18.81	15.29	14.68		15.35	20.68	19.51
College and above	12.89	8.85	6.13	4.87		6.14	11.18	9.42
House wife
Yes	2.60	2.21	2.15	2.06	0.002	2.11	2.41	2.24	0.013
No	97.40	97.79	97.85	97.94	0.002	97.89	97.59	97.76	0.013
Chinese Ethnic group
Chinese Han	95.36	95.02	95.41	95.64	0.015	94.98	96.47	94.55	<0.001
Others	4.64	4.98	4.59	4.36	0.015	5.02	3.53	5.45	<0.001
Maternal risk factors (%)
Previous preterm delivery
No	99.75	99.83	99.62	99.59	<0.001	99.79	99.83	99.78	0.239
Yes	0.25	0.17	0.38	0.41	<0.001	0.21	0.17	0.22	0.239
Preconception hypertension
No	98.41	97.99	95.74	90.05	<0.001	97.29	98.08	97.71	<0.001
Yes	1.59	2.01	4.26	9.95	<0.001	2.71	1.92	2.29	<0.001
Anemia
No	84.54	85.99	85.21	87.38	<0.001	83.98	83.41	87.58	<0.001
Yes	15.46	14.01	14.79	12.62	<0.001	16.02	16.59	12.42	<0.001
Diabetes mellitus
No	98.34	98.77	98.05	96.84	<0.001	98.63	98.28	98.76	<0.001
Yes	1.66	1.23	1.95	3.16	<0.001	1.37	1.72	1.24	<0.001
Dislike vegetables
No	99.24	99.37	99.17	99.11	0.004	99.27	99.34	99.34	0.286
Yes	0.76	0.63	0.83	0.89	0.004	0.73	0.66	0.66	0.286
Preconception alcohol use
No	96.79	97.01	97.20	97.32	0.080	97.43	96.83	96.89	<0.001
Yes	3.21	2.99	2.80	2.68	0.080	2.57	3.17	3.11	<0.001
Preconception Tobacco use
No	99.63	99.70	99.57	99.31	<0.001	99.70	99.58	99.70	0.001
Yes	0.37	0.30	0.43	0.69	<0.001	0.30	0.42	0.30	0.001
Preterm delivery
No	94.11	94.57	94.05	93.69	0.001	92.08	94.98	95.23	<0.001
Yes	5.89	5.43	5.95	6.31	0.001	7.92	5.02	4.77	<0.001

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ISSN: 1471-2393

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