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Table 4 Selected clinical characteristics of index women and their pregnancies

From: The Norwegian preeclampsia family cohort study: a new resource for investigating genetic aspects and heritability of preeclampsia and related phenotypes

 

Pregnancies among index women

Preeclamptic pregnancies among index women

Non-preeclamptic pregnancies among index women

(Pregnancies with birth data n = 547) (Live birth pregnancies n = 544)

(n = 326)

(n = 214)

Age at delivery no. (mean ± standard deviation)

 1

24.5 ± 4.9 (n = 214)

24.8 ± 5 (n = 181)

23.1 ± 4.0 (n = 32)

 2

27.7 ± 4.5 (n = 194)

28.2 ± 4.4 (n = 89)

27.3 ± 4.7 (n = 103)

 3

30.6 ± 4.6 (n = 95)

31.1 ± 4.9 (n = 44)

30.2 ± 4.4 (n = 51)

 4

31.9 ± 3.2 (n = 27)

31.5 ± 4.1 (n = 10)

32.1 ± 2.6 (n = 17)

 5

33.2 ± 4.2 (n = 9)

31.5 ± 6.4 (n = 2)

33.7 ± 3.9 (n = 7)

Multiple pregnancy

n = 7

n = 4

n = 3

Mode of delivery

 Vaginala,b

n = 396

n = 215

n = 178

 Inducedb

n = 196

n = 160

n = 35

 Cesarean sectiona

n = 136

n = 102

n = 34

 Plannedc

n = 37

n = 20

n = 17

 Acutec

n = 99

n = 82

n = 17

Placenta weightd

591 ± 164 (264 valid, 283 missing)

560 ± 166 (173 valid, 155 missing)

653 ± 138 (89 valid, 125 missing)

Birth weighte

3189 ± 843 (528 valid, 19 missing)

2981 ± 874 (321 valid, 7 missing)

3526 ± 645 (204 valid, 10 missing)

Neonate sex

 Male

n = 261

n = 152

n = 106

 Female

n = 288

n = 180

n = 108

Experienced abortions

 Spontaneous

n = 89

  

 Induced

n = 43

  
  1. aComparing the number of vaginal deliveries with the number of cesarean sections in preeclamptic pregnancies versus non-preeclamtic pregnancies there is a significant difference using Pearson’s chi square analysis in a 2 × 2 contingency table. The number of cesarean sections was significantly higher in preeclamptic pregnancies (p = 3.2 × 10−5)
  2. bComparing the number of induced vaginal deliveries with the number of non-induced vagnial deliveries in preeclamptic pregnancies versus non-preeclamtic pregnancies there is a significant difference using Pearson’s chi square analysis in a 2 × 2 contingency table. The number of induced vaginal deliveries was significantly higher in preeclamptic pregnancies (p = 3.2 × 10−27)
  3. cComparing the number of acute cesarean sections with the number of planned cesarean sections in preeclamptic pregnancies versus non-preeclamtic pregnancies there is a significant difference using Pearson’s chi square analysis in a 2 × 2 contingency table. The number of acute cesarean sections was significantly higher in preeclamptic pregnancies (p = 5.6 × 10−4)
  4. dThe placenta weight in preeclamptic pregnancies was significantly lower compared with non-preeclamptic pregnancies using t-test statistics (p = 0.9 × 10−5)
  5. eThe birth weight of neonates born from preeclamptic pregnancies was significantly lower compared with non-preeclamptic pregnancies using t-test statistics (p = 1.9 × 10−15)