Table 2 Overview of data collected from participants
1. Questionnaire | |
a.Maternal characteristics | Age at attendance, exposed for preeclampsia, parity, smoking habits and medication during pregnancy |
b.Paternal characteristics | Age at attendance, exposed for preeclampsia, fathered a preeclamptic pregnancy |
c.Pregnancy and birth characteristics | Due date, date of birth, preeclampsia, gestational hypertension, gestational diabetes, eclampsia, HELLP, mode of delivery (vaginal or cesarean section), labor onset (spontaneous or induction), placental weight, experienced abortions |
d.Offspring characteristics | Sex, birth weight, twin or multiple |
e.Self-reported personal disease history focusing on preeclampsia, diabetes and cardiovascular disease | Time of onset of disease, duration of disease |
f.Self-reported family disease history focusing on preeclampsia, diabetes and cardiovascular disease | |
2. Physical measurements at attendance | |
a.Height | |
b.Weight | |
c.Waist circumference | |
3. Biological samples (blood) | |
a.EDTA – 1 × 10 ml | Buffy coat for DNA analyses (genetic and epigenetic), plasma for protein/metabolites/nutrients analyses |
b.Serum Separating Tube (SST) – 1 × 10 ml | Serum for protein/metabolites/nutrients analyses |
c.Tempus Blood RNA tubes – 1 × 9 ml (6 ml RNA stabilizing fluid) | Whole blood for RNA analyses (gene expression and qualitative analyses) |