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Table 1 Baseline event rates used in the economic evaluation

From: Prevention of postpartum haemorrhage: cost consequences analysis of misoprostol in low-resource settings

Baseline incidence

Point estimate

Low

High

Placebo event rates (Tunçalp [14])

PPH

16.0 %

12.0 %

27.3 %

Severe PPH

3.0 %

0.7 %

9.7 %

Additional uterotonics

7.2 %

0.7 %

38.7 %

Blood transfusion

0.8 %

0.5 %

0.9 %

Shivering

10.8 %

0.0 %

17.3 %

Fever

1.6 %

0.0 %

4.3 %

Oxytocin event rates (Tunçalp [14])

PPH

12.4 %

0.4 %

17.3 %

Severe PPH

2.7 %

0.0 %

6.5 %

Additional uterotonics

11.1 %

4.4 %

14.0 %

Blood transfusion

1.1 %

0.0 %

1.6 %

Shivering

6.0 %

0.0 %

40.4 %

Fever

1.0 %

0.00 %

7.00 %

Placebo event rates; alternative values: home birth setting (Hundley [23])

PPH

12.2 %

NC

NC

Severe PPH

1.2 %

NC

NC

Additional uterotonics

5.4 %

NC

NC

Blood transfusion

2.9 %

NC

NC

Shivering

17.8 %

NC

NC

Fever

13.8 %

NC

NC

  1. Abbreviations: NC not calculated. Placebo event rates from Tunçalp [14] based on the misoprostol 600 μg vs placebo comparison; oxytocin event rates from the misoprostol 600 μg vs injectable uterotonics comparison. Point estimates derived from an average across all trials; Low values derived from the trial with the lowest estimate; High values derived from the trial with the highest estimate