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Table 1 The total prevalence of malformations at birth before and after prenatal screening was formally instituted

From: Changes in detection of birth defects and perinatal mortality after introduction of prenatal ultrasound screening in the Kola Peninsula (North-West Russia): combination of two birth registries

Number or Prevalence 1973-2000 2001-2011 p-value1
Number of newborns included in the analysis 23 822 6626  
Number of newborns with BD 816 283  
Prevalence of BD at birth (per 1000 newborns)2 34.2 (31.9-36.5)2 42.8 (38.0-47.7) 0.001
Number of newborns with forms of BD requiring mandatory reporting 175 48  
Prevalence at birth of BD forms requiring mandatory reporting (per 1000 newborns)2 7.3 (6.3-8.4) 7.3 (5.2-9.4) 0.500
  1. 1 Chi-squared test
  2. 2 95 % confidence intervals are given in parentheses