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Table 4 Odds ratio, with 95 % confidence interval, of having at least one agreement between questionnaire and prescription redemption database

From: Medication use during pregnancy, gestational age and date of delivery: agreement between maternal self-reports and health database information in a cohort

 

Agreement between questionnaire and databasea

 

At least 1 (N = 266)

None (N = 375)

Univariate

Multivariatea

Multivariateb

n

%

n

%

Odds Ratio

95 % CIb

Odds Ratio

95 % CIb

Odds Ratio

95 % CIb

Age at delivery (years)

 

<25

20

7.6

18

4.8

1.71

0.87; 3.39

2.25

1.06; 4.79

2.11

0.90; 4.93

25-29

27

10.1

61

16.3

0.68

0.41; 1.14

0.67

0.39; 1.14

0.57

0.31; 1.04

30-34c

110

41.3

170

45.3

1.00

- -

1.00

- -

1.00

- -

35-39

81

30.4

106

28.3

1.18

0.81; 1.72

1.33

0.90; 1.97

0.97

0.62; 1.52

40+

28

10.6

20

5.3

2.16

1.16; 4.03

2.25

1.19; 4.26

2.34

1.15; 4.76

Country of origina

 

Italyc

245

92.1

341

90.9

1.00

- -

1.00

- -

1.00

- -

Other

19

7.1

30

8.0

0.88

0.48; 1.60

0.88

0.46; 1.67

0.83

0.30; 1.63

Level of education

 

< High school

39

14.7

71

19.0

0.59

0.37; 0.95

0.64

0.38; 1.08

0.64

0.35; 1.19

High school

118

44.4

186

49.7

0.69

0.48; 0.97

0.75

0.53; 1.09

0.89

0.59; 1.35

Universityc

108

40.6

117

31.3

1.00

- -

1.00

- -

1.00

- -

Smoking statusa

 

Ex-smoker, having quit during or after pregnancy

17

6.4

41

10.9

0.50

0.27; 0.91

0.48

0.26; 0.90

0.61

0.30; 1.24

Ex-smoker, having quit before pregnancy

56

21.2

80

21.3

0.85

0.57; 1.26

0.85

0.56; 1.29

0.91

0.57; 1.45

Current smoker

19

7.2

40

10.7

0.57

0.32; 1.03

0.66

0.36; 1.21

0.78

0.39; 1.56

Never smokerc

172

65.1

208

55.5

1.00

- -

1.00

- -

1.00

- -

Prior pregnancies

 

None

138

51.9

165

44.0

1.37

1.00; 1.88

1.50

1.07; 2.11

1.52

1.03; 2.24

At least onec

128

48.1

210

56.0

1.00

- -

1.00

- -

1.00

- -

Comorbidities during pregnancyd

 

At least one

202

75.9

286

76.3

1.79

1.25; 2.55

1.55

1.01; 2.37

1.10

0.66; 1.81

Nonec

61

22.9

89

23.7

1.00

- -

1.00

- -

1.00

- -

Number of medications reported in questionnaire

 

0

78

29.3

269

71.7

0.26

0.17; 0.39

- -

- -

0.26

0.17; 0.41

 

1c

80

30.1

72

19.2

1.00

- -

- -

- -

1.00

- -

 

2

65

24.4

23

6.1

2.54

1.43; 4.51

- -

- -

2.53

1.39; 4.59

 

3 or more

43

16.2

11

2.9

3.52

1.69; 7.34

- -

- -

3.81

1.74; 8.34

Marital status

 

Marriedc

242

91.0

332

88.5

1.00

- -

- -

- -

- -

- -

Single

23

8.6

38

10.1

0.83

0.48; 1.43

- -

- -

- -

- -

Time of questionnaire completion

 

Pre-delivery

127

47.7

204

54.4

0.77

0.56; 1.05

- -

- -

- -

- -

Post-deliveryc

139

52.3

171

45.6

1.00

- -

- -

- -

- -

- -

Prenatal care visits (number)

 

<7

47

17.7

75

20.0

0.89

0.54; 1.47

- -

- -

- -

- -

7

41

15.4

57

15.2

0.96

0.60; 1.52

- -

- -

- -

- -

8

52

19.5

75

20.0

0.92

0.61; 1.41

- -

- -

- -

- -

9 + c

126

47.4

168

44.8

1.00

- -

- -

- -

- -

- -

Ultrasound imaging during pregnancy (number)

 

<4

66

24.8

98

26.1

0.87

0.56; 1.33

- -

- -

- -

- -

4

50

18.8

60

16.0

1.07

0.66; 1.73

- -

- -

- -

- -

5-7

73

27.5

118

31.5

0.79

0.52; 1.21

- -

- -

- -

- -

8 + c

77

28.9

99

26.4

1.00

- -

- -

- -

- -

- -

  1. a Adjusted by age at delivery, level of education, prior pregnancies, smoking status, comorbidities during pregnancy, country of origin
  2. b 95 % CI = 95 % confidence interval
  3. c Reference category
  4. d It includes the following comorbidities occurring only during the pregnancy or before and during the pregnancy: diabetes, asthma, allergy, epilepsy, hypertension, vomit, hypothyroidism, hyperthyroidism, lupus, rheumatic diseases, urinary infections, infections, fever, seizures, anaemia, cardiovascular diseases, and neurological diseases